GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:NUSA

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) nusA (ECO:0000255 with HAMAP-Rule:MF_00945)
Protein Name(s) Transcription termination/antitermination protein NusA (ECO:0000255 with HAMAP-Rule:MF_00945)

N utilization substance protein A Transcription termination/antitermination L factor

External Links
UniProt P0AFF6
EMBL X00513
U18997
U00096
AP009048
PIR E65107
RefSeq NP_417638.1
WP_001031057.1
PDB 1U9L
1WCL
1WCN
2JZB
2KWP
5LM9
5MS0
6FLQ
PDBsum 1U9L
1WCL
1WCN
2JZB
2KWP
5LM9
5MS0
6FLQ
ProteinModelPortal P0AFF6
SMR P0AFF6
BioGrid 4261878
DIP DIP-47857N
IntAct P0AFF6
STRING 511145.b3169
SWISS-2DPAGE P0AFF6
EPD P0AFF6
jPOST P0AFF6
PaxDb P0AFF6
PRIDE P0AFF6
EnsemblBacteria AAC76203
BAE77215
GeneID 947682
KEGG ecj:JW3138
eco:b3169
PATRIC fig|1411691.4.peg.3561
EchoBASE EB0659
EcoGene EG10665
eggNOG ENOG4105CHV
COG0195
HOGENOM HOG000006394
InParanoid P0AFF6
KO K02600
PhylomeDB P0AFF6
BioCyc EcoCyc:EG10665-MONOMER
ECOL316407:JW3138-MONOMER
EvolutionaryTrace P0AFF6
PRO PR:P0AFF6
Proteomes UP000000318
UP000000625
GO GO:0005829
GO:0001000
GO:0003700
GO:0000166
GO:0019904
GO:0003723
GO:0031564
GO:0001125
Gene3D 3.30.1480.10
3.30.300.20
HAMAP MF_00945_B
InterPro IPR010995
IPR015946
IPR025249
IPR009019
IPR012340
IPR030842
IPR036555
IPR022967
IPR003029
IPR013735
IPR010214
IPR010213
PANTHER PTHR22648
Pfam PF13184
PF08529
PF00575
SMART SM00316
SUPFAM SSF47794
SSF50249
SSF54814
SSF69705
TIGRFAMs TIGR01953
TIGR01954
PROSITE PS50084
PS50126

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0001000

bacterial-type RNA polymerase core enzyme binding

PMID:9659923[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

involved_in

GO:0001125

transcription termination from bacterial-type RNA polymerase promoter

PMID:9659923[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

enables

GO:0019904

protein domain specific binding

PMID:9659923[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P03045

F

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10665
PANTHER:PTN000505391
UniProtKB:P9WIV3

P

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10665
PANTHER:PTN000505391

C

Seeded From UniProt

GO:0051259

protein complex oligomerization

PMID:23907089[3]

ECO:0000314

direct assay evidence used in manual assertion

P

In Figure 1, it is shown that under heat shock conditions NusA can form stable high molecular weight(HMW)oligomers.

complete
CACAO 8807

involved_in

GO:0031564

transcription antitermination

PMID:16631197[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:18304323[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:17272300[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:15911532[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010995

F

Seeded From UniProt

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003029

F

Seeded From UniProt

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013735
InterPro:IPR036555

F

Seeded From UniProt

enables

GO:0003723

RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009019
InterPro:IPR010213
InterPro:IPR025249

F

Seeded From UniProt

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030842

P

Seeded From UniProt

involved_in

GO:0031554

regulation of DNA-templated transcription, termination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013735
InterPro:IPR036555

P

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030842

P

Seeded From UniProt

enables

GO:0003723

RNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

F

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

C

Seeded From UniProt

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

P

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0889

P

Seeded From UniProt

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0806

P

Seeded From UniProt

enables

GO:0001000

bacterial-type RNA polymerase core enzyme binding

PMID:9659923[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

involved_in

GO:0001125

transcription termination from bacterial-type RNA polymerase promoter

PMID:9659923[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

enables

GO:0019904

protein domain specific binding

PMID:9659923[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P03045

F

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10665
PANTHER:PTN000505391
UniProtKB:P9WIV3

P

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10665
PANTHER:PTN000505391

C

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:21742261[8]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0A7Z4

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:19402753[9]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0A8U6

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:18996995[10]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q47155

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:15690043[11]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0A8U6

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:15690043[11]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0A7Z4

F

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

PMID:16631197[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:18304323[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:17272300[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005829

cytosol

PMID:15911532[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010995

F

Seeded From UniProt

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003029

F

Seeded From UniProt

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013735
InterPro:IPR036555

F

Seeded From UniProt

enables

GO:0003723

RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009019
InterPro:IPR010213
InterPro:IPR025249

F

Seeded From UniProt

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030842

P

Seeded From UniProt

involved_in

GO:0031554

regulation of DNA-templated transcription, termination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013735
InterPro:IPR036555

P

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030842

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0889

P

Seeded From UniProt

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0806

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

enables

GO:0003723

RNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

F

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

C

Seeded From UniProt

involved_in

GO:0006353

DNA-templated transcription, termination

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

P

Seeded From UniProt

involved_in

GO:0031564

transcription antitermination

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000165451

P

Seeded From UniProt


edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Mogridge, J et al. (1998) Independent ligand-induced folding of the RNA-binding domain and two functionally distinct antitermination regions in the phage lambda N protein. Mol. Cell 1 265-75 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. ↑ Li, K et al. (2013) Escherichia coli transcription termination factor NusA: heat-induced oligomerization and chaperone activity. Sci Rep 3 2347 PubMed GONUTS page
  4. ↑ 4.0 4.1 Kim, HC et al. (2006) Role of E.coli NusA in phage HK022 Nun-mediated transcription termination. J. Mol. Biol. 359 10-21 PubMed GONUTS page
  5. ↑ 5.0 5.1 Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  6. ↑ 6.0 6.1 Watt, RM et al. (2007) Visualizing the proteome of Escherichia coli: an efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes. Nucleic Acids Res. 35 e37 PubMed GONUTS page
  7. ↑ 7.0 7.1 Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
  8. ↑ Schweimer, K et al. (2011) NusA interaction with the α subunit of E. coli RNA polymerase is via the UP element site and releases autoinhibition. Structure 19 945-54 PubMed GONUTS page
  9. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed GONUTS page
  10. ↑ Cohen, SE et al. (2009) Transcriptional modulator NusA interacts with translesion DNA polymerases in Escherichia coli. J. Bacteriol. 191 665-72 PubMed GONUTS page
  11. ↑ 11.0 11.1 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=ECOLI:NUSA&oldid=5959601"