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ECOLI:MUKB

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) mukB
Protein Name(s) Chromosome partition protein MukB

Structural maintenance of chromosome-related protein

External Links
UniProt P22523
EMBL X57550
D31701
U00096
AP009048
D26440
PIR C64832
JH0228
RefSeq NP_415444.1
YP_489196.1
PDB 1QHL
2WMM
3IBP
4MN4
PDBsum 1QHL
2WMM
3IBP
4MN4
ProteinModelPortal P22523
SMR P22523
DIP DIP-10273N
IntAct P22523
MINT MINT-1225884
STRING 511145.b0924
PaxDb P22523
PRIDE P22523
EnsemblBacteria AAC74010
BAA35670
GeneID 12932693
945549
KEGG ecj:Y75_p0896
eco:b0924
PATRIC 32117061
EchoBASE EB0613
EcoGene EG10618
eggNOG COG3096
HOGENOM HOG000278243
InParanoid P22523
KO K03632
OMA HAMMFDL
OrthoDB EOG62C98M
PhylomeDB P22523
BioCyc EcoCyc:EG10618-MONOMER
ECOL316407:JW0907-MONOMER
EvolutionaryTrace P22523
PRO PR:P22523
Proteomes UP000000318
UP000000625
Genevestigator P22523
GO GO:0000796
GO:0005737
GO:0009295
GO:0005524
GO:0003677
GO:0005525
GO:0042802
GO:0051301
GO:0030261
GO:0007059
GO:0006260
GO:0007062
HAMAP MF_01800
InterPro IPR012090
IPR007406
IPR027417
Pfam PF04310
PIRSF PIRSF005246
SUPFAM SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007062

sister chromatid cohesion

PMID:14517265[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007059

chromosome segregation

PMID:17824928[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007059

chromosome segregation

PMID:14517265[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

PMID:1989883[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:1464330[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

PMID:16740950[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

PMID:18376412[6]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007059

chromosome segregation

PMID:16133165[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

PMID:1464330[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

PMID:1464330[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:1464330[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0000796

condensin complex

PMID:16740950[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007406
InterPro:IPR012090

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007406
InterPro:IPR012090

F

Seeded From UniProt

complete

involved_in

GO:0007059

chromosome segregation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007406
InterPro:IPR012090

P

Seeded From UniProt

complete

part_of

GO:0009295

nucleoid

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007406
InterPro:IPR012090

C

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007406
InterPro:IPR012090

P

Seeded From UniProt

complete

involved_in

GO:0007059

chromosome segregation

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084196

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084196

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084196

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084196

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084196

C

Seeded From UniProt

complete

involved_in

GO:0007059

chromosome segregation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0159

P

Seeded From UniProt

complete

involved_in

GO:0030261

chromosome condensation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0226

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0132

P

Seeded From UniProt

complete

part_of

GO:0009295

nucleoid

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0187

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Kruse, T et al. (2003) Dysfunctional MreB inhibits chromosome segregation in Escherichia coli. EMBO J. 22 5283-92 PubMed GONUTS page
  2. ↑ Danilova, O et al. (2007) MukB colocalizes with the oriC region and is required for organization of the two Escherichia coli chromosome arms into separate cell halves. Mol. Microbiol. 65 1485-92 PubMed GONUTS page
  3. ↑ Niki, H et al. (1991) The new gene mukB codes for a 177 kd protein with coiled-coil domains involved in chromosome partitioning of E. coli. EMBO J. 10 183-93 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 Niki, H et al. (1992) E.coli MukB protein involved in chromosome partition forms a homodimer with a rod-and-hinge structure having DNA binding and ATP/GTP binding activities. EMBO J. 11 5101-9 PubMed GONUTS page
  5. ↑ 5.0 5.1 Wang, Q et al. (2006) Chromosome condensation in the absence of the non-SMC subunits of MukBEF. J. Bacteriol. 188 4431-41 PubMed GONUTS page
  6. ↑ Cui, Y et al. (2008) MukB acts as a macromolecular clamp in DNA condensation. Nat. Struct. Mol. Biol. 15 411-8 PubMed GONUTS page
  7. ↑ Adachi, S et al. (2005) Localization of replication forks in wild-type and mukB mutant cells of Escherichia coli. Mol. Genet. Genomics 274 264-71 PubMed GONUTS page
  8. ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
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