ECOLI:MUG

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	mug (synonyms: ygjF)
Protein Name(s)	G/U mismatch-specific DNA glycosylase Double-strand-specific uracil glycosylase Mismatch-specific uracil DNA-glycosylase MUG
External Links
UniProt	P0A9H1
EMBL	U28379 U00096 AP009048 J01687
PIR	B65095
RefSeq	NP_417540.1 YP_491260.1
PDB	1MTL 1MUG 1MWI 1MWJ
PDBsum	1MTL 1MUG 1MWI 1MWJ
ProteinModelPortal	P0A9H1
SMR	P0A9H1
IntAct	P0A9H1
STRING	511145.b3068
PaxDb	P0A9H1
PRIDE	P0A9H1
EnsemblBacteria	AAC76104 BAE77119
GeneID	12933393 947560
KEGG	ecj:Y75_p2994 eco:b3068
PATRIC	32121552
EchoBASE	EB2576
EcoGene	EG12717
eggNOG	COG3663
HOGENOM	HOG000264684
InParanoid	P0A9H1
KO	K03649
OMA	RPGNRFW
OrthoDB	EOG68H872
PhylomeDB	P0A9H1
BioCyc	EcoCyc:EG12717-MONOMER ECOL316407:JW3040-MONOMER MetaCyc:EG12717-MONOMER
EvolutionaryTrace	P0A9H1
PRO	PR:P0A9H1
Proteomes	UP000000318 UP000000625
Genevestigator	P0A9H1
GO	GO:0005737 GO:0003677 GO:0008263 GO:0006285
Gene3D	3.40.470.10
HAMAP	MF_01956
InterPro	IPR023502 IPR015637 IPR005122
PANTHER	PTHR12159
Pfam	PF03167
SMART	SM00986
SUPFAM	SSF52141

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	PMID:8878487	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
	GO:0004844	uracil DNA N-glycosylase activity	PMID:20852254	ECO:0000314			F		Figure 2A: Shows cleavage products of uracil-containing DNA substrates by MUG. Figure 3A: Shows kinetic analysis of MUG on uracil-containing substrates.	complete
involved_in	GO:0006285	base-excision repair, AP site formation	PMID:8878487	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015637 InterPro:IPR023502	P		Seeded From UniProt	complete
enables	GO:0019104	DNA N-glycosylase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015637 InterPro:IPR023502	F		Seeded From UniProt	complete
enables	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000033420	F		Seeded From UniProt	complete
involved_in	GO:0006285	base-excision repair, AP site formation	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000033420	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000033420	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0228 UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
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References

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