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ECOLI:MTNN
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | mtnN (synonyms: mtn, pfs, yadA) | |
| Protein Name(s) | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
MTA/SAH nucleosidase MTAN 5'-methylthioadenosine nucleosidase MTA nucleosidase P46 S-adenosylhomocysteine nucleosidase AdoHcy nucleosidase SAH nucleosidase SRH nucleosidase | |
| External Links | ||
| UniProt | P0AF12 | |
| EMBL | M31772 U24438 M83735 U70214 U00096 AP009048 | |
| PIR | S45227 | |
| RefSeq | NP_414701.1 WP_000689844.1 | |
| PDB | 1JYS 1NC1 1NC3 1Y6Q 1Y6R 1Z5N 1Z5O 1Z5P 3O4V 4WKC 4YML | |
| PDBsum | 1JYS 1NC1 1NC3 1Y6Q 1Y6R 1Z5N 1Z5O 1Z5P 3O4V 4WKC 4YML | |
| ProteinModelPortal | P0AF12 | |
| SMR | P0AF12 | |
| BioGrid | 4260991 | |
| DIP | DIP-10270N | |
| IntAct | P0AF12 | |
| STRING | 511145.b0159 | |
| BindingDB | P0AF12 | |
| ChEMBL | CHEMBL2866 | |
| DrugBank | DB02933 DB00173 DB02281 | |
| SWISS-2DPAGE | P0AF12 | |
| EPD | P0AF12 | |
| PaxDb | P0AF12 | |
| PRIDE | P0AF12 | |
| EnsemblBacteria | AAC73270 BAB96736 | |
| GeneID | 948542 | |
| KEGG | ecj:JW0155 eco:b0159 | |
| PATRIC | 32115427 | |
| EchoBASE | EB1082 | |
| EcoGene | EG11090 | |
| eggNOG | ENOG4105DUF COG0775 | |
| HOGENOM | HOG000259346 | |
| InParanoid | P0AF12 | |
| KO | K01243 | |
| OMA | LLERCKP | |
| PhylomeDB | P0AF12 | |
| BioCyc | EcoCyc:EG11090-MONOMER MetaCyc:EG11090-MONOMER | |
| BRENDA | 3.2.2.30 3.2.2.9 | |
| UniPathway | UPA00904 | |
| EvolutionaryTrace | P0AF12 | |
| PRO | PR:P0AF12 | |
| Proteomes | UP000000318 UP000000625 | |
| GO | GO:0005829 GO:0008782 GO:0008930 GO:0019509 GO:0019284 GO:0009164 | |
| Gene3D | 3.40.50.1580 | |
| HAMAP | MF_01684 | |
| InterPro | IPR010049 IPR000845 | |
| Pfam | PF01048 | |
| SUPFAM | SSF53167 | |
| TIGRFAMs | TIGR01704 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0019284 |
L-methionine salvage from S-adenosylmethionine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11090 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008930 |
methylthioadenosine nucleosidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11090 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008782 |
adenosylhomocysteine nucleosidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11090 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11090 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019284 |
L-methionine salvage from S-adenosylmethionine |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008930 |
methylthioadenosine nucleosidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008782 |
adenosylhomocysteine nucleosidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008782 |
adenosylhomocysteine nucleosidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008930 |
methylthioadenosine nucleosidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009116 |
nucleoside metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009164 |
nucleoside catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019509 |
L-methionine salvage from methylthioadenosine |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008782 |
adenosylhomocysteine nucleosidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008782 |
adenosylhomocysteine nucleosidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000084108 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008930 |
methylthioadenosine nucleosidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000084108 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019284 |
L-methionine salvage from S-adenosylmethionine |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000084108 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009086 |
methionine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019509 |
L-methionine salvage from methylthioadenosine |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00904 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Lee, JE et al. (2001) Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases. Structure 9 941-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Cornell, KA & Riscoe, MK (1998) Cloning and expression of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase: identification of the pfs gene product. Biochim. Biophys. Acta 1396 8-14 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
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