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ECOLI:MQSA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) mqsA (synonyms: ygiT)
Protein Name(s) Antitoxin MqsA
External Links
UniProt Q46864
EMBL U28377
U00096
AP009048
PIR C65089
RefSeq NP_417493.1
YP_491213.1
PDB 2KZ8
3FMY
3GA8
3GN5
3HI2
3O9X
PDBsum 2KZ8
3FMY
3GA8
3GN5
3HI2
3O9X
ProteinModelPortal Q46864
SMR Q46864
DIP DIP-12226N
IntAct Q46864
STRING 511145.b3021
PRIDE Q46864
EnsemblBacteria AAC76057
BAE77077
GeneID 12930253
945814
KEGG ecj:Y75_p2947
eco:b3021
PATRIC 32121456
EchoBASE EB2840
EcoGene EG13022
eggNOG COG1396
HOGENOM HOG000151625
KO K13655
OMA GIWDEES
OrthoDB EOG6CK7RV
BioCyc EcoCyc:G7571-MONOMER
ECOL316407:JW2989-MONOMER
MetaCyc:G7571-MONOMER
EvolutionaryTrace Q46864
PRO PR:Q46864
Proteomes UP000000318
UP000000625
Genevestigator Q46864
GO GO:0046872
GO:0043565
GO:0006355
GO:0006351
Gene3D 1.10.260.40
InterPro IPR001387
IPR010982
IPR022452
IPR022453
SMART SM00530
SUPFAM SSF47413
TIGRFAMs TIGR03830
TIGR03831
PROSITE PS50943

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0043565

sequence-specific DNA binding

PMID:19690171[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:19943910[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0045892

negative regulation of transcription, DNA-dependent

PMID:20233923[3]

ECO:0000314

P

Fig. 3D: MqsA (YgiT) acts as a transcriptional repressor of the mqsR-ygiT operon, counteracting the effects of the MqsR toxin.

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010982

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001387

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yamaguchi, Y et al. (2009) MqsR, a crucial regulator for quorum sensing and biofilm formation, is a GCU-specific mRNA interferase in Escherichia coli. J. Biol. Chem. 284 28746-53 PubMed GONUTS page
  2. Christensen-Dalsgaard, M et al. (2010) Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol. Microbiol. 75 333-48 PubMed GONUTS page
  3. Kasari, V et al. (2010) The Escherichia coli mqsR and ygiT genes encode a new toxin-antitoxin pair. J. Bacteriol. 192 2908-19 PubMed GONUTS page