GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:MLTB

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) mltB
Protein Name(s) Membrane-bound lytic murein transglycosylase B

35 kDa soluble lytic transglycosylase Murein hydrolase B Slt35

External Links
UniProt P41052
EMBL U18785
U00096
AP009048
J02708
PIR A65050
RefSeq NP_417181.1
YP_490910.1
PDB 1D0K
1D0L
1D0M
1LTM
1QDR
1QDT
1QUS
1QUT
PDBsum 1D0K
1D0L
1D0M
1LTM
1QDR
1QDT
1QUS
1QUT
ProteinModelPortal P41052
SMR P41052
DIP DIP-10221N
IntAct P41052
MINT MINT-1257117
STRING 511145.b2701
BindingDB P41052
ChEMBL CHEMBL2046262
CAZy GH103
PaxDb P41052
PRIDE P41052
EnsemblBacteria AAC75743
BAA16563
GeneID 12933085
947184
KEGG ecj:Y75_p2639
eco:b2701
PATRIC 32120800
EchoBASE EB2561
EcoGene EG12699
eggNOG COG2951
HOGENOM HOG000257828
InParanoid P41052
KO K08305
OMA RYMGNFR
OrthoDB EOG6R87H7
PhylomeDB P41052
BioCyc EcoCyc:G7410-MONOMER
ECOL316407:JW2671-MONOMER
MetaCyc:G7410-MONOMER
EvolutionaryTrace P41052
PRO PR:P41052
Proteomes UP000000318
UP000000625
Genevestigator P41052
GO GO:0009279
GO:0016837
GO:0008933
GO:0071555
GO:0009252
InterPro IPR023346
IPR011757
PANTHER PTHR30163
Pfam PF13406
SUPFAM SSF53955
TIGRFAMs TIGR02282
PROSITE PS51257

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008933

lytic transglycosylase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12699
PANTHER:PTN001575318
UniProtKB:Q9HVX3
UniProtKB:Q9HX24

F

Seeded From UniProt

complete

enables

GO:0031402

sodium ion binding

PMID:10570954[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

PMID:7476170[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009253

peptidoglycan catabolic process

PMID:7476170[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009253

peptidoglycan catabolic process

PMID:7789526[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009253

peptidoglycan catabolic process

PMID:18700763[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008933

lytic transglycosylase activity

PMID:23421439[6]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008933

lytic transglycosylase activity

PMID:18700763[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008932

lytic endotransglycosylase activity

PMID:23421439[6]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

PMID:10570954[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0030288

outer membrane-bounded periplasmic space

PMID:15174130[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0071555

cell wall organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0961

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0998
UniProtKB-SubCell:SL-0040

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 van Asselt, EJ & Dijkstra, BW (1999) Binding of calcium in the EF-hand of Escherichia coli lytic transglycosylase Slt35 is important for stability. FEBS Lett. 458 429-35 PubMed GONUTS page
  3. 3.0 3.1 Ehlert, K et al. (1995) Cloning and expression of a murein hydrolase lipoprotein from Escherichia coli. Mol. Microbiol. 16 761-8 PubMed GONUTS page
  4. Dijkstra, AJ et al. (1995) Cloning and controlled overexpression of the gene encoding the 35 kDa soluble lytic transglycosylase from Escherichia coli. FEBS Lett. 366 115-8 PubMed GONUTS page
  5. 5.0 5.1 Suvorov, M et al. (2008) Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall. J. Am. Chem. Soc. 130 11878-9 PubMed GONUTS page
  6. 6.0 6.1 Lee, M et al. (2013) Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall. J. Am. Chem. Soc. 135 3311-4 PubMed GONUTS page
  7. Gonnet, P et al. (2004) Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Proteomics 4 1597-613 PubMed GONUTS page