ECOLI:METN

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	metN (ECO:0000255 with HAMAP-Rule:MF_01719) (synonyms: abc)
Protein Name(s)	Methionine import ATP-binding protein MetN (ECO:0000255 with HAMAP-Rule:MF_01719)
External Links
UniProt	P30750
EMBL	D15061 U70214 U00096 AP009048 L08626
PIR	G64744
RefSeq	NP_414741.1 YP_488502.1
PDB	3DHW 3DHX 3TUI 3TUJ 3TUZ
PDBsum	3DHW 3DHX 3TUI 3TUJ 3TUZ
ProteinModelPortal	P30750
SMR	P30750
DIP	DIP-9027N
IntAct	P30750
MINT	MINT-1223626
STRING	511145.b0199
TCDB	3.A.1.24.1
PaxDb	P30750
EnsemblBacteria	AAC73310 BAA77876
GeneID	12930761 944896
KEGG	ecj:Y75_p0196 eco:b0199
PATRIC	32115511
EchoBASE	EB1578
EcoGene	EG11621
eggNOG	COG1135
InParanoid	P30750
KO	K02071
OMA	GIMLAEM
OrthoDB	EOG6T7N3V
PhylomeDB	P30750
BioCyc	EcoCyc:ABC-MONOMER ECOL316407:JW0195-MONOMER MetaCyc:ABC-MONOMER
EvolutionaryTrace	P30750
PRO	PR:P30750
Proteomes	UP000000318 UP000000625
Genevestigator	P30750
GO	GO:0043190 GO:0009276 GO:0015424 GO:0005524 GO:0016887 GO:0048474 GO:0006200
Gene3D	3.40.50.300
InterPro	IPR003593 IPR026253 IPR012692 IPR003439 IPR017871 IPR017908 IPR018449 IPR027417
PANTHER	PTHR24220:SF186
Pfam	PF00005 PF09383
SMART	SM00382 SM00930
SUPFAM	SSF52540
TIGRFAMs	TIGR02314
PROSITE	PS00211 PS50893 PS51264

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0048473	D-methionine transport	PMID:12218041^[1]	ECO:0000315			P	Figure 3A shows metN (abc) mutant is unable to grow when treated with D-methionine, proving taht the protein is necessary for D-methionine transport in E.coli.	complete CACAO 10791
involved_in	GO:0048473	D-methionine transport	PMID:12218041^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0048474	D-methionine transmembrane transporter activity	PMID:18621668^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	PMID:18621668^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	PMID:18621668^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	PMID:18621668^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	PMID:12819857^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0015191	L-methionine transmembrane transporter activity	PMID:12819857^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	PMID:12218041^[1]	ECO:0000255	match to sequence model evidence used in manual assertion		F	Seeded From UniProt	Missing: with/from
enables	GO:0005524	ATP binding	PMID:12169620^[4]	ECO:0000255	match to sequence model evidence used in manual assertion		F	Seeded From UniProt	Missing: with/from
involved_in	GO:0003333	amino acid transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0015424	P	Seeded From UniProt	complete
involved_in	GO:0006855	drug transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015191	P	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0042626	P	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0042626	P	Seeded From UniProt	complete
involved_in	GO:1902475	L-alpha-amino acid transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015191	P	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003439 InterPro:IPR012692 InterPro:IPR017871 InterPro:IPR026253	F	Seeded From UniProt	complete
part_of	GO:0009276	Gram-negative-bacterium-type cell wall	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012692	C	Seeded From UniProt	complete
involved_in	GO:0015821	methionine transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026253	P	Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003439 InterPro:IPR017871	F	Seeded From UniProt	complete
enables	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026253	F	Seeded From UniProt	complete
involved_in	GO:0048473	D-methionine transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012692	P	Seeded From UniProt	complete
enables	GO:0048474	D-methionine transmembrane transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012692	F	Seeded From UniProt	complete
involved_in	GO:0006865	amino acid transport	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000101056	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000101056	C	Seeded From UniProt	complete
enables	GO:0015424	amino acid-transporting ATPase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000101056	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
involved_in	GO:0006865	amino acid transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0029	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0997 UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0037	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Merlin, C et al. (2002) The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ). J. Bacteriol. 184 5513-7 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Kadaba, NS et al. (2008) The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Science 321 250-3 PubMed GONUTS page
↑ ^3.0 ^3.1 Zhang, Z et al. (2003) A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily. Arch. Microbiol. 180 88-100 PubMed GONUTS page
↑ Gál, J et al. (2002) The metD D-methionine transporter locus of Escherichia coli is an ABC transporter gene cluster. J. Bacteriol. 184 4930-2 PubMed GONUTS page

[PMID:12218041-1] 1.0 ^1.1 ^1.2 Merlin, C et al. (2002) The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ). J. Bacteriol. 184 5513-7 PubMed GONUTS page

[PMID:18621668-2] 2.0 ^2.1 ^2.2 ^2.3 Kadaba, NS et al. (2008) The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Science 321 250-3 PubMed GONUTS page

[PMID:12819857-3] 3.0 ^3.1 Zhang, Z et al. (2003) A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily. Arch. Microbiol. 180 88-100 PubMed GONUTS page

[PMID:12169620-4] Gál, J et al. (2002) The metD D-methionine transporter locus of Escherichia coli is an ABC transporter gene cluster. J. Bacteriol. 184 4930-2 PubMed GONUTS page

[1]

[2]

[3]

[4]

ECOLI:METN

Contents

Annotations

Notes

References

a

b

d

e

g

h

l

m

n

p

t

x

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools