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ECOLI:METI

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) metI (synonyms: yaeE)
Protein Name(s) D-methionine transport system permease protein MetI
External Links
UniProt P31547
EMBL D15061
U70214
U00096
AP009048
PIR F64744
RefSeq NP_414740.1
YP_488501.1
PDB 3DHW
3TUI
3TUJ
3TUZ
PDBsum 3DHW
3TUI
3TUJ
3TUZ
ProteinModelPortal P31547
SMR P31547
DIP DIP-11198N
IntAct P31547
STRING 511145.b0198
TCDB 3.A.1.24.1
EnsemblBacteria AAC73309
BAA77875
GeneID 12930760
944894
KEGG ecj:Y75_p0195
eco:b0198
PATRIC 32115509
EchoBASE EB1688
EcoGene EG11737
eggNOG COG2011
HOGENOM HOG000222815
InParanoid P31547
KO K02072
OMA QIIANPK
OrthoDB EOG6P073X
PhylomeDB P31547
BioCyc EcoCyc:METI-MONOMER
ECOL316407:JW0194-MONOMER
MetaCyc:METI-MONOMER
EvolutionaryTrace P31547
PRO PR:P31547
Proteomes UP000000318
UP000000625
Genevestigator P31547
GO GO:0016021
GO:0005886
GO:0006865
Gene3D 1.10.3720.10
InterPro IPR000515
Pfam PF00528
SUPFAM SSF161098
PROSITE PS50928

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048473

D-methionine transport

PMID:12218041[1]

ECO:0000315

P

Figure 3A shows that metI (yaeE) mutant is not able to grow when treated with D-methionine, proving that the protein is necessary for D-methionine transport in E.coli.

complete
CACAO 10790

involved_in

GO:0048473

D-methionine transport

PMID:12218041[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048473

D-methionine transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11737
PANTHER:PTN000765164

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10007
EcoGene:EG11737
PANTHER:PTN000765163

C

Seeded From UniProt

complete

part_of

GO:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

PMID:18621668[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0015191

L-methionine transmembrane transporter activity

PMID:12819857[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:18621668[3]

ECO:0000255

match to sequence model evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

part_of

GO:0005886

plasma membrane

PMID:17309111[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15919996[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006855

drug transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015191

P

Seeded From UniProt

complete

involved_in

GO:1902475

L-alpha-amino acid transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015191

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000515

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000515

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-KW:KW-0997
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006865

amino acid transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0029

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Merlin, C et al. (2002) The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ). J. Bacteriol. 184 5513-7 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Kadaba, NS et al. (2008) The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Science 321 250-3 PubMed GONUTS page
  4. Zhang, Z et al. (2003) A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily. Arch. Microbiol. 180 88-100 PubMed GONUTS page
  5. Zhang, N et al. (2007) Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Proteomics 7 484-93 PubMed GONUTS page
  6. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page