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ECOLI:MEPS
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | mepS (synonyms: spr, yeiV) | |
Protein Name(s) | Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase
Lipoprotein Spr Murein hydrolase MepS | |
External Links | ||
UniProt | P0AFV4 | |
EMBL | D86610 U00096 AP009048 | |
PIR | F64986 | |
RefSeq | NP_416680.1 WP_000241011.1 | |
PDB | 2K1G | |
PDBsum | 2K1G | |
ProteinModelPortal | P0AFV4 | |
SMR | P0AFV4 | |
BioGrid | 4261093 | |
IntAct | P0AFV4 | |
STRING | 511145.b2175 | |
MEROPS | C40.004 | |
PaxDb | P0AFV4 | |
PRIDE | P0AFV4 | |
EnsemblBacteria | AAC75236 BAA15983 | |
GeneID | 946686 | |
KEGG | ecj:JW2163 eco:b2175 | |
PATRIC | 32119705 | |
EchoBASE | EB3829 | |
EcoGene | EG14076 | |
eggNOG | ENOG4107TT5 COG0791 | |
HOGENOM | HOG000229978 | |
InParanoid | P0AFV4 | |
KO | K13694 | |
OMA | GRHIGIY | |
OrthoDB | EOG60CWQW | |
PhylomeDB | P0AFV4 | |
BioCyc | EcoCyc:G7147-MONOMER ECOL316407:JW2163-MONOMER MetaCyc:G7147-MONOMER | |
UniPathway | UPA00963 | |
EvolutionaryTrace | P0AFV4 | |
PRO | PR:P0AFV4 | |
Proteomes | UP000000318 UP000000625 | |
GO | GO:0009279 GO:0008234 GO:0004175 GO:0045227 GO:0071555 GO:0000270 GO:0009254 | |
Gene3D | 3.90.1720.10 | |
InterPro | IPR000064 | |
Pfam | PF00877 | |
PROSITE | PS51257 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0009254 |
peptidoglycan turnover |
ECO:0000315 |
P |
Fig 2, Fig 5 C & D, Fig 6 |
complete | |||||
involved_in |
GO:0009254 |
peptidoglycan turnover |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0009279 |
cell outer membrane |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
Pfam:PF00877 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004175 |
endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004175 |
endopeptidase activity |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
Pfam:PF00877 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000270 |
peptidoglycan metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0009279 |
cell outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008234 |
cysteine-type peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071555 |
cell wall organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045227 |
capsule polysaccharide biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00963 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Singh, SK et al. (2012) Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis of Escherichia coli K12. Mol. Microbiol. 86 1036-51 PubMed GONUTS page
- ↑ Aramini, JM et al. (2008) Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad. Biochemistry 47 9715-7 PubMed GONUTS page
- ↑ Anantharaman, V & Aravind, L (2003) Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes. Genome Biol. 4 R11 PubMed GONUTS page