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ECOLI:MANA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) manA (synonyms: pmi)
Protein Name(s) Mannose-6-phosphate isomerase

Phosphohexomutase Phosphomannose isomerase PMI

External Links
UniProt P00946
EMBL M15380
U00096
AP009048
U35067
PIR A01172
RefSeq NP_416130.3
YP_489876.1
ProteinModelPortal P00946
SMR P00946
DIP DIP-10153N
IntAct P00946
MINT MINT-1241491
STRING 511145.b1613
SWISS-2DPAGE P00946
PaxDb P00946
PRIDE P00946
EnsemblBacteria AAC74685
BAA15361
GeneID 12931261
944840
KEGG ecj:Y75_p1589
eco:b1613
PATRIC 32118528
EchoBASE EB0561
EcoGene EG10566
eggNOG COG1482
HOGENOM HOG000241278
InParanoid P00946
KO K01809
OMA VMKMEVP
OrthoDB EOG6130B2
PhylomeDB P00946
BioCyc EcoCyc:MANNPISOM-MONOMER
ECOL316407:JW1605-MONOMER
MetaCyc:MANNPISOM-MONOMER
PRO PR:P00946
Proteomes UP000000318
UP000000625
Genevestigator P00946
GO GO:0005737
GO:0004476
GO:0008270
GO:0009242
GO:0009298
GO:0019309
Gene3D 2.60.120.10
InterPro IPR001250
IPR016305
IPR018050
IPR014710
IPR011051
PANTHER PTHR10309
Pfam PF01238
PIRSF PIRSF001480
PRINTS PR00714
SUPFAM SSF51182
TIGRFAMs TIGR00218
PROSITE PS00965
PS00966

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0009298

GDP-mannose biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10566
MGI:MGI:97075
PANTHER:PTN000034017
SGD:S000000805

P

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000034017
SGD:S000000805

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10566
PANTHER:PTN000034017
UniProtKB:O05898

C

Seeded From UniProt

complete

enables

GO:0004476

mannose-6-phosphate isomerase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000189115
EcoGene:EG10566
MGI:MGI:97075
PANTHER:PTN000034017
SGD:S000000805
TAIR:locus:2019748
TAIR:locus:2076864
UniProtKB:Q66WM4

F

Seeded From UniProt

complete

involved_in

GO:0000032

cell wall mannoprotein biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000034017
SGD:S000000805

P

Seeded From UniProt

complete

involved_in

GO:0019309

mannose catabolic process

PMID:4862193[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009298

GDP-mannose biosynthetic process

PMID:4862193[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009242

colanic acid biosynthetic process

PMID:4862193[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004476

mannose-6-phosphate isomerase activity

PMID:5335965[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004476

mannose-6-phosphate isomerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001250
InterPro:IPR016305
InterPro:IPR018050

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001250

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001250

F

Seeded From UniProt

complete

involved_in

GO:0009298

GDP-mannose biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016305

P

Seeded From UniProt

complete

enables

GO:0004476

mannose-6-phosphate isomerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.3.1.8

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Markovitz, A et al. (1967) Genetic and biochemical studies on mannose-negative mutants that are deficient in phosphomannose isomerase in Escherichia coli K-12. J. Bacteriol. 94 1492-6 PubMed GONUTS page
  3. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  4. Kang, S & Markovitz, A (1967) Induction of capsular polysaccharide synthesis by rho-fluorophenylalanine in Escherichia coli wild type and strains with altered phenylalanyl soluble ribonucleic acid synthetase. J. Bacteriol. 93 584-91 PubMed GONUTS page