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ECOLI:LSRK

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) lsrK (ECO:0000255 with HAMAP-Rule:MF_02053) (synonyms: ydeV)
Protein Name(s) Autoinducer-2 kinase (ECO:0000255 with HAMAP-Rule:MF_02053)

AI-2 kinase (ECO:0000255 with HAMAP-Rule:MF_02053)

External Links
UniProt P77432
EMBL U00096
AP009048
S82185
PIR B64905
RefSeq NP_416028.3
WP_000113108.1
ProteinModelPortal P77432
SMR P77432
BioGrid 4260224
DIP DIP-11687N
IntAct P77432
MINT MINT-1251018
STRING 511145.b1511
PaxDb P77432
PRIDE P77432
EnsemblBacteria AAC74584
BAA15191
GeneID 946069
KEGG ecj:JW1504
eco:b1511
PATRIC 32118318
EchoBASE EB3565
EcoGene EG13804
eggNOG ENOG4108EMV
COG1070
HOGENOM HOG000092677
InParanoid P77432
KO K11216
OMA FSDAMHF
PhylomeDB P77432
BioCyc EcoCyc:G6798-MONOMER
MetaCyc:G6798-MONOMER
PRO PR:P77432
Proteomes UP000000318
UP000000625
GO GO:0005737
GO:0071518
GO:0016773
GO:0005975
GO:0009372
GO:0044010
HAMAP MF_02053
InterPro IPR033676
IPR000577
IPR018485
IPR018484
Pfam PF02782
PF00370
PIRSF PIRSF000538

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0071518

autoinducer-2 kinase activity

PMID:16597969[1]

ECO:0000314

F

Autoinducer 2(AI-2) is generated in large part by LuxS. AI-2 aids in quorum-sensing.

complete
CACAO 12460

enables

GO:0071518

autoinducer-2 kinase activity

PMID:20025244[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0071518

autoinducer-2 kinase activity

PMID:15601708[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8ZKQ6

F

Seeded From UniProt

complete

involved_in

GO:0044010

single-species biofilm formation

PMID:17557827[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009372

quorum sensing

PMID:15601708[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000577
InterPro:IPR018484
InterPro:IPR018485

P

Seeded From UniProt

complete

involved_in

GO:0009372

quorum sensing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033676

P

Seeded From UniProt

complete

enables

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000577
InterPro:IPR018484
InterPro:IPR018485

F

Seeded From UniProt

complete

enables

GO:0071518

autoinducer-2 kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033676

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000270455

C

Seeded From UniProt

complete

enables

GO:0071518

autoinducer-2 kinase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000270455

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Challan Belval, S et al. (2006) Assessment of the roles of LuxS, S-ribosyl homocysteine, and autoinducer 2 in cell attachment during biofilm formation by Listeria monocytogenes EGD-e. Appl. Environ. Microbiol. 72 2644-50 PubMed GONUTS page
  2. Roy, V et al. (2010) Cross species quorum quenching using a native AI-2 processing enzyme. ACS Chem. Biol. 5 223-32 PubMed GONUTS page
  3. 3.0 3.1 Xavier, KB & Bassler, BL (2005) Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. J. Bacteriol. 187 238-48 PubMed GONUTS page
  4. Li, J et al. (2007) Quorum sensing in Escherichia coli is signaled by AI-2/LsrR: effects on small RNA and biofilm architecture. J. Bacteriol. 189 6011-20 PubMed GONUTS page