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ECOLI:LPXH

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) lpxH (ECO:0000255 with HAMAP-Rule:MF_00575) (synonyms: ybbF)
Protein Name(s) UDP-2,3-diacylglucosamine hydrolase (ECO:0000255 with HAMAP-Rule:MF_00575)

UDP-2,3-diacylglucosamine diphosphatase (ECO:0000255 with HAMAP-Rule:MF_00575)

External Links
UniProt P43341
EMBL AF311865
U82664
U00096
AP009048
M19657
PIR C64784
RefSeq NP_415057.1
YP_488813.1
ProteinModelPortal P43341
DIP DIP-10125N
IntAct P43341
STRING 511145.b0524
EnsemblBacteria AAC73626
BAE76301
GeneID 12933823
949053
KEGG ecj:Y75_p0510
eco:b0524
PATRIC 32116208
EchoBASE EB2532
EcoGene EG12666
eggNOG COG2908
HOGENOM HOG000261930
InParanoid P43341
KO K03269
OMA FMHGNRD
OrthoDB EOG6FNHR2
PhylomeDB P43341
BioCyc EcoCyc:EG12666-MONOMER
ECOL316407:JW0513-MONOMER
MetaCyc:EG12666-MONOMER
UniPathway UPA00359
PRO PR:P43341
Proteomes UP000000318
UP000000625
Genevestigator P43341
GO GO:0005737
GO:0019897
GO:0008758
GO:0009245
Gene3D 3.60.21.10
HAMAP MF_00575
InterPro IPR004843
IPR029052
IPR010138
Pfam PF00149
SUPFAM SSF56300
TIGRFAMs TIGR01854

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0009245

lipid A biosynthetic process

PMID:12000770[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008758

UDP-2,3-diacylglucosamine hydrolase activity

PMID:12000770[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0019897

extrinsic component of plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12666
PANTHER:PTN002169200

C

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12666
PANTHER:PTN002169200
UniProtKB:Q9I2V0

P

Seeded From UniProt

complete

enables

GO:0008758

UDP-2,3-diacylglucosamine hydrolase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12666
PANTHER:PTN002169200
UniProtKB:P44046
UniProtKB:Q9I2V0

F

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

PMID:12000771[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008758

UDP-2,3-diacylglucosamine hydrolase activity

PMID:12000771[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0019897

extrinsic component of plasma membrane

PMID:12000771[3]

ECO:0000269

experimental evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010138

C

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010138

P

Seeded From UniProt

complete

enables

GO:0016462

pyrophosphatase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010138

F

Seeded From UniProt

complete

enables

GO:0008758

UDP-2,3-diacylglucosamine hydrolase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000031212

F

Seeded From UniProt

complete

enables

GO:0030145

manganese ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000031212

F

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000031212

P

Seeded From UniProt

complete

part_of

GO:0019897

extrinsic component of plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000031212

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0997
UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0441

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Babinski, KJ et al. (2002) The Escherichia coli gene encoding the UDP-2,3-diacylglucosamine pyrophosphatase of lipid A biosynthesis. J. Biol. Chem. 277 25937-46 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 Babinski, KJ et al. (2002) Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in an Escherichia coli mutant lacking the lpxH gene. J. Biol. Chem. 277 25947-56 PubMed GONUTS page