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ECOLI:LIGB

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) ligB (synonyms: yicF)
Protein Name(s) DNA ligase B

Polydeoxyribonucleotide synthase [NAD(+)] B

External Links
UniProt P25772
EMBL L10328
U00096
AP009048
M84400
PIR A65166
RefSeq NP_418104.2
YP_491787.1
ProteinModelPortal P25772
SMR P25772
IntAct P25772
STRING 511145.b3647
PaxDb P25772
PRIDE P25772
DNASU 948164
EnsemblBacteria AAC76671
BAE77646
GeneID 12933573
948164
KEGG ecj:Y75_p3527
eco:b3647
PATRIC 32122781
EchoBASE EB1310
EcoGene EG11334
eggNOG COG0272
HOGENOM HOG000267776
KO K01972
OMA WIQPKVD
OrthoDB EOG6TTVM9
PhylomeDB P25772
BioCyc EcoCyc:EG11334-MONOMER
ECOL316407:JW3622-MONOMER
MetaCyc:EG11334-MONOMER
PRO PR:P25772
Proteomes UP000000318
UP000000625
Genevestigator P25772
GO GO:0005829
GO:0003911
GO:0006288
GO:0006266
GO:0006260
Gene3D 2.40.50.140
HAMAP MF_01587
InterPro IPR018239
IPR020923
IPR013839
IPR013840
IPR012340
IPR004150
IPR010994
Pfam PF01653
PF03120
SMART SM00532
SUPFAM SSF47781
SSF50249
PROSITE PS01055
PS01056

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006288

base-excision repair, DNA ligation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10534
PANTHER:PTN000121726

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10534
PANTHER:PTN000121726
UniProtKB:P9WNV1

C

Seeded From UniProt

complete

enables

GO:0003911

DNA ligase (NAD+) activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10534
EcoGene:EG11334
PANTHER:PTN000121726
UniProtKB:P9WNV1

F

Seeded From UniProt

complete

enables

GO:0003911

DNA ligase (NAD+) activity

PMID:11812821[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0051103

DNA ligation involved in DNA repair

PMID:28700629[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006266

DNA ligation

PMID:11812821[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003911

DNA ligase (NAD+) activity

PMID:11812821[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003911

DNA ligase (NAD+) activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004150
InterPro:IPR013839
InterPro:IPR013840
InterPro:IPR020923

F

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020923

P

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004150

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004150

P

Seeded From UniProt

complete

enables

GO:0003911

DNA ligase (NAD+) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:6.5.1.2

F

Seeded From UniProt

complete

enables

GO:0003911

DNA ligase (NAD+) activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000079167

F

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000079167

P

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Sriskanda, V & Shuman, S (2001) A second NAD(+)-dependent DNA ligase (LigB) in Escherichia coli. Nucleic Acids Res. 29 4930-4 PubMed GONUTS page
  3. Bodine, TJ et al. (2017) Escherichia coli DNA ligase B may mitigate damage from oxidative stress. PLoS ONE 12 e0180800 PubMed GONUTS page