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ECOLI:LGT
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | lgt (synonyms: umpA) | |
| Protein Name(s) | Prolipoprotein diacylglyceryl transferase | |
| External Links | ||
| UniProt | P60955 | |
| EMBL | U12289 U29581 U00096 AP009048 J01710 | |
| PIR | A56149 | |
| RefSeq | NP_417305.1 YP_491033.1 | |
| ProteinModelPortal | P60955 | |
| STRING | 511145.b2828 | |
| EnsemblBacteria | AAC75867 BAE76897 | |
| GeneID | 12934282 947303 | |
| KEGG | ecj:Y75_p2762 eco:b2828 | |
| PATRIC | 32121074 | |
| EchoBASE | EB2049 | |
| EcoGene | EG12128 | |
| eggNOG | COG0682 | |
| HOGENOM | HOG000098666 | |
| InParanoid | P60955 | |
| KO | K13292 | |
| OMA | HWYGLAY | |
| OrthoDB | EOG6MH5CQ | |
| PhylomeDB | P60955 | |
| BioCyc | EcoCyc:EG12128-MONOMER ECOL316407:JW2796-MONOMER MetaCyc:EG12128-MONOMER | |
| UniPathway | UPA00664 | |
| PRO | PR:P60955 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P60955 | |
| GO | GO:0016021 GO:0005887 GO:0008961 GO:0042158 GO:0009249 | |
| HAMAP | MF_01147 | |
| InterPro | IPR001640 | |
| Pfam | PF01790 | |
| TIGRFAMs | TIGR00544 | |
| PROSITE | PS01311 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008961 |
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity |
ECO:0000315 |
F |
These results (Fig. 1 and Table 1) show that E. coli umpA mutants (strains SK634, SK635, and SK636) were defective in diacylglyceryl modification of prolipoprotein because of defective diacylglyceryl transferase. Defective modification of prolipoprotein in umpA mutants was confirmed by in vitro analysis of prolipoprotein modification activity. |
complete | |||||
|
involved_in |
GO:0042158 |
lipoprotein biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042158 |
lipoprotein biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009898 |
cytoplasmic side of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008961 |
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008961 |
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042158 |
lipoprotein biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000071004 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042158 |
lipoprotein biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000071004 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008961 |
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000071004 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Gan, K et al. (1995) The umpA gene of Escherichia coli encodes phosphatidylglycerol:prolipoprotein diacylglyceryl transferase (lgt) and regulates thymidylate synthase levels through translational coupling. J. Bacteriol. 177 1879-82 PubMed GONUTS page
- ↑ 2.0 2.1 Sankaran, K & Wu, HC (1994) Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol. J. Biol. Chem. 269 19701-6 PubMed GONUTS page
- ↑ Selvan, AT & Sankaran, K () Localization and characterization of prolipoprotein diacylglyceryl transferase (Lgt) critical in bacterial lipoprotein biosynthesis. Biochimie 90 1647-55 PubMed GONUTS page
- ↑ Pailler, J et al. (2012) Phosphatidylglycerol::prolipoprotein diacylglyceryl transferase (Lgt) of Escherichia coli has seven transmembrane segments, and its essential residues are embedded in the membrane. J. Bacteriol. 194 2142-51 PubMed GONUTS page
- ↑ Williams, MG et al. (1989) Identification and genetic mapping of the structural gene for an essential Escherichia coli membrane protein. J. Bacteriol. 171 565-8 PubMed GONUTS page
- ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page
