GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:KEFF

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) kefF (ECO:0000255 with HAMAP-Rule:MF_01414) (synonyms: yabF)
Protein Name(s) Glutathione-regulated potassium-efflux system ancillary protein KefF (ECO:0000255 with HAMAP-Rule:MF_01414)

Quinone oxidoreductase KefF (ECO:0000255 with HAMAP-Rule:MF_01414)

External Links
UniProt P0A754
EMBL U00096
AP009048
PIR F64725
RefSeq NP_414588.1
YP_488352.1
PDB 3EYW
3L9W
3L9X
PDBsum 3EYW
3L9W
3L9X
ProteinModelPortal P0A754
SMR P0A754
DIP DIP-35822N
IntAct P0A754
STRING 511145.b0046
TCDB 2.A.37.1.1
EnsemblBacteria AAC73157
BAB96614
GeneID 12933207
944767
KEGG ecj:Y75_p0046
eco:b0046
PATRIC 32115191
EchoBASE EB1528
EcoGene EG11568
eggNOG COG2249
HOGENOM HOG000149972
InParanoid P0A754
KO K11746
OMA VNADTEH
OrthoDB EOG628F94
PhylomeDB P0A754
BioCyc EcoCyc:EG11568-MONOMER
ECOL316407:JW0045-MONOMER
MetaCyc:EG11568-MONOMER
EvolutionaryTrace P0A754
PRO PR:P0A754
Proteomes UP000000318
UP000000625
Genevestigator P0A754
GO GO:0005886
GO:0009055
GO:0010181
GO:0003955
GO:0032414
GO:1901381
GO:0006813
Gene3D 3.40.50.360
HAMAP MF_01414
InterPro IPR003680
IPR029039
IPR023948
Pfam PF02525
SUPFAM SSF52218

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009055

electron carrier activity

PMID:17679694[1]

ECO:0000315

F

Fig.4

complete

involved_in

GO:0032414

positive regulation of ion transmembrane transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11568
PANTHER:PTN000785312

P

Seeded From UniProt

complete

enables

GO:0010181

FMN binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11568
PANTHER:PTN000785312

F

Seeded From UniProt

complete

enables

GO:0009055

electron transfer activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11568
PANTHER:PTN000785312

F

Seeded From UniProt

complete

enables

GO:0003955

NAD(P)H dehydrogenase (quinone) activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11568
PANTHER:PTN000785312

F

Seeded From UniProt

complete

enables

GO:0009055

electron transfer activity

PMID:17679694[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0032414

positive regulation of ion transmembrane transporter activity

PMID:11053405[3]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P03819

P

Seeded From UniProt

complete

involved_in

GO:0032414

positive regulation of ion transmembrane transporter activity

PMID:21742892[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0010181

FMN binding

PMID:21742892[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003955

NAD(P)H dehydrogenase (quinone) activity

PMID:21742892[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0022900

electron transport chain

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0009055

P

Seeded From UniProt

complete

involved_in

GO:0022900

electron transport chain

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0009055

P

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023948

P

Seeded From UniProt

complete

enables

GO:0003955

NAD(P)H dehydrogenase (quinone) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.6.5.2

F

Seeded From UniProt

complete

enables

GO:0003955

NAD(P)H dehydrogenase (quinone) activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000034429

F

Seeded From UniProt

complete

enables

GO:0010181

FMN binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000034429

F

Seeded From UniProt

complete

involved_in

GO:1901381

positive regulation of potassium ion transmembrane transport

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000034429

P

Seeded From UniProt

complete

involved_in

GO:0032414

positive regulation of ion transmembrane transporter activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000034429

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0997
UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Fujisawa, M et al. (2007) Three two-component transporters with channel-like properties have monovalent cation/proton antiport activity. Proc. Natl. Acad. Sci. U.S.A. 104 13289-94 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Miller, S et al. (2000) Identification of an ancillary protein, YabF, required for activity of the KefC glutathione-gated potassium efflux system in Escherichia coli. J. Bacteriol. 182 6536-40 PubMed GONUTS page
  4. 4.0 4.1 4.2 Lyngberg, L et al. (2011) KefF, the regulatory subunit of the potassium efflux system KefC, shows quinone oxidoreductase activity. J. Bacteriol. 193 4925-32 PubMed GONUTS page