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ECOLI:K6PF2
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | pfkB | |
| Protein Name(s) | 6-phosphofructokinase isozyme 2
Phosphofructokinase-2 | |
| External Links | ||
| UniProt | P06999 | |
| EMBL | K02500 U00096 AP009048 K00128 | |
| PIR | C64931 | |
| RefSeq | NP_416237.3 YP_489984.1 | |
| PDB | 3CQD 3N1C 3UMO 3UMP 3UQD 3UQE | |
| PDBsum | 3CQD 3N1C 3UMO 3UMP 3UQD 3UQE | |
| ProteinModelPortal | P06999 | |
| SMR | P06999 | |
| DIP | DIP-10465N | |
| MINT | MINT-8178151 | |
| STRING | 511145.b1723 | |
| SWISS-2DPAGE | P06999 | |
| PaxDb | P06999 | |
| PRIDE | P06999 | |
| EnsemblBacteria | AAC74793 BAA15500 | |
| GeneID | 12934082 946230 | |
| KEGG | ecj:Y75_p1698 eco:b1723 | |
| PATRIC | 32118753 | |
| EchoBASE | EB0694 | |
| EcoGene | EG10700 | |
| eggNOG | COG1105 | |
| HOGENOM | HOG000265281 | |
| KO | K16370 | |
| OMA | NVARTIH | |
| OrthoDB | EOG61KBKF | |
| PhylomeDB | P06999 | |
| BioCyc | EcoCyc:6PFK-2-MONOMER ECOL316407:JW5280-MONOMER MetaCyc:6PFK-2-MONOMER | |
| SABIO-RK | P06999 | |
| UniPathway | UPA00109 | |
| EvolutionaryTrace | P06999 | |
| PRO | PR:P06999 | |
| Genevestigator | P06999 | |
| GO | GO:0003872 GO:0005524 GO:0042802 GO:0000287 GO:0009024 GO:0046835 GO:0006974 GO:0006096 | |
| Gene3D | 3.40.1190.20 | |
| InterPro | IPR002173 IPR011611 IPR029056 IPR017583 | |
| Pfam | PF00294 | |
| PIRSF | PIRSF000535 | |
| SUPFAM | SSF53613 | |
| TIGRFAMs | TIGR03168 | |
| PROSITE | PS00583 PS00584 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0008443 |
phosphofructokinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10337 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10700 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003872 |
6-phosphofructokinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10700 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009024 |
tagatose-6-phosphate kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003872 |
6-phosphofructokinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046835 |
carbohydrate phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008443 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0061615 |
glycolytic process through fructose-6-phosphate |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0003872 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0061615 |
glycolytic process through fructose-6-phosphate |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0003872 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0061615 |
glycolytic process through fructose-6-phosphate |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003872 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0005975 |
carbohydrate metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003872 |
6-phosphofructokinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006096 |
glycolytic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0324 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Baez, M et al. (2011) Folding kinetic pathway of phosphofructokinase-2 from Escherichia coli: a homodimeric enzyme with a complex domain organization. FEBS Lett. 585 2158-64 PubMed GONUTS page
- ↑ Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page
- ↑ 4.0 4.1 Babul, J (1978) Phosphofructokinases from Escherichia coli. Purification and characterization of the nonallosteric isozyme. J. Biol. Chem. 253 4350-5 PubMed GONUTS page
- ↑ Vinopal, RT & Fraenkel, DG (1975) PfkB and pfkC loci of Escherichia coli. J. Bacteriol. 122 1153-61 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
- ↑ Parducci, RE et al. (2006) Evidence for a catalytic Mg2+ ion and effect of phosphate on the activity of Escherichia coli phosphofructokinase-2: regulatory properties of a ribokinase family member. Biochemistry 45 9291-9 PubMed GONUTS page
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