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ECOLI:ISPA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | ispA | |
| Protein Name(s) | Farnesyl diphosphate synthase
FPP synthase (2E,6E)-farnesyl diphosphate synthase Geranyltranstransferase | |
| External Links | ||
| UniProt | P22939 | |
| EMBL | D00694 U82664 U00096 AP009048 | |
| PIR | JQ0665 | |
| RefSeq | NP_414955.1 YP_488713.1 | |
| PDB | 1RQI 1RQJ | |
| PDBsum | 1RQI 1RQJ | |
| ProteinModelPortal | P22939 | |
| SMR | P22939 | |
| DIP | DIP-10044N | |
| IntAct | P22939 | |
| MINT | MINT-1233182 | |
| STRING | 511145.b0421 | |
| BindingDB | P22939 | |
| ChEMBL | CHEMBL1075078 | |
| SWISS-2DPAGE | P22939 | |
| PaxDb | P22939 | |
| PRIDE | P22939 | |
| EnsemblBacteria | AAC73524 BAE76201 | |
| GeneID | 12930843 945064 | |
| KEGG | ecj:Y75_p0409 eco:b0421 | |
| PATRIC | 32115991 | |
| EchoBASE | EB0503 | |
| EcoGene | EG10508 | |
| eggNOG | COG0142 | |
| HOGENOM | HOG000009101 | |
| InParanoid | P22939 | |
| KO | K00795 | |
| OMA | QNRINHF | |
| OrthoDB | EOG6TN43W | |
| PhylomeDB | P22939 | |
| BioCyc | EcoCyc:FPPSYN-MONOMER ECOL316407:JW0411-MONOMER MetaCyc:FPPSYN-MONOMER | |
| BRENDA | 2.5.1.1 | |
| SABIO-RK | P22939 | |
| EvolutionaryTrace | P22939 | |
| PRO | PR:P22939 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P22939 | |
| GO | GO:0005737 GO:0004161 GO:0004337 GO:0046872 GO:0045337 GO:0033384 | |
| Gene3D | 1.10.600.10 | |
| InterPro | IPR000092 IPR017446 IPR008949 | |
| PANTHER | PTHR12001 | |
| Pfam | PF00348 | |
| SUPFAM | SSF48576 | |
| PROSITE | PS00723 PS00444 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0045337 |
farnesyl diphosphate biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0033384 |
geranyl diphosphate biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004337 |
geranyltranstransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004161 |
dimethylallyltranstransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008299 |
isoprenoid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004337 |
geranyltranstransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008299 |
isoprenoid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Fujisaki, S et al. (1989) Isolation and characterization of an Escherichia coli mutant having temperature-sensitive farnesyl diphosphate synthase. J. Bacteriol. 171 5654-8 PubMed GONUTS page
- ↑ Fujisaki, S et al. (2005) Disruption of the structural gene for farnesyl diphosphate synthase in Escherichia coli. J. Biochem. 137 395-400 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
- ↑ 4.0 4.1 Lee, PC et al. (2005) Directed evolution of Escherichia coli farnesyl diphosphate synthase (IspA) reveals novel structural determinants of chain length specificity. Metab. Eng. 7 18-26 PubMed GONUTS page
