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ECOLI:ILVD
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | ilvD (ECO:0000255 with HAMAP-Rule:MF_00012) | |
Protein Name(s) | Dihydroxy-acid dehydratase (ECO:0000255 with HAMAP-Rule:MF_00012)
DAD (ECO:0000255 with HAMAP-Rule:MF_00012) | |
External Links | ||
UniProt | P05791 | |
EMBL | X04890 M10313 M87049 U00096 AP009048 M32253 X02413 K03503 | |
PIR | A27310 | |
RefSeq | YP_026248.1 YP_491667.1 | |
ProteinModelPortal | P05791 | |
SMR | P05791 | |
DIP | DIP-10021N | |
IntAct | P05791 | |
MINT | MINT-1302071 | |
STRING | 511145.b3771 | |
SWISS-2DPAGE | P05791 | |
PaxDb | P05791 | |
PRIDE | P05791 | |
EnsemblBacteria | AAT48208 BAE77526 | |
GeneID | 12934335 948277 | |
KEGG | ecj:Y75_p3404 eco:b3771 | |
PATRIC | 32123037 | |
EchoBASE | EB0491 | |
EcoGene | EG10496 | |
eggNOG | COG0129 | |
HOGENOM | HOG000173155 | |
InParanoid | P05791 | |
KO | K01687 | |
OMA | QGRNMAG | |
OrthoDB | EOG6MSS24 | |
PhylomeDB | P05791 | |
BioCyc | EcoCyc:DIHYDROXYACIDDEHYDRAT-MONOMER ECOL316407:JW5605-MONOMER MetaCyc:DIHYDROXYACIDDEHYDRAT-MONOMER | |
UniPathway | UPA00047 UPA00049 | |
PRO | PR:P05791 | |
Proteomes | UP000000318 UP000000625 | |
Genevestigator | P05791 | |
GO | GO:0051539 GO:0004160 GO:0051536 GO:0046872 GO:0009097 GO:0009099 | |
HAMAP | MF_00012 | |
InterPro | IPR015928 IPR004404 IPR000581 IPR020558 | |
PANTHER | PTHR21000 | |
Pfam | PF00920 | |
SUPFAM | SSF52016 | |
TIGRFAMs | TIGR00110 | |
PROSITE | PS00886 PS00887 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0004160 |
dihydroxy-acid dehydratase activity |
ECO:0000314 |
F |
Fig. 1. As the concentration of the enzyme increases, concentration of the product of the reaction increases as well. The reaction is seen on the first page in the first paragraph. |
complete | |||||
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10496 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009099 |
valine biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004160 |
dihydroxy-acid dehydratase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004160 |
dihydroxy-acid dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009082 |
branched-chain amino acid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004160 |
dihydroxy-acid dehydratase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009099 |
valine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000001403 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000001403 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004160 |
dihydroxy-acid dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000001403 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009082 |
branched-chain amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00047 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009099 |
valine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00049 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 MYERS, JW (1961) Dihydroxy acid dehydrase: an enzyme involved in the biosynthesis of isoleucine and valine. J. Biol. Chem. 236 1414-8 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Flint, DH et al. (1993) The role and properties of the iron-sulfur cluster in Escherichia coli dihydroxy-acid dehydratase. J. Biol. Chem. 268 14732-42 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page