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ECOLI:IBPA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) ibpA (synonyms: hslT, htpN)
Protein Name(s) Small heat shock protein IbpA

16 kDa heat shock protein A

External Links
UniProt P0C054
EMBL M94104
L10328
U00096
AP009048
PIR A45245
RefSeq NP_418142.1
YP_491748.1
ProteinModelPortal P0C054
DIP DIP-47849N
IntAct P0C054
MINT MINT-1219330
STRING 511145.b3687
SWISS-2DPAGE P0C054
PaxDb P0C054
PRIDE P0C054
EnsemblBacteria AAC76710
BAE77607
GeneID 12933596
948200
KEGG ecj:Y75_p3486
eco:b3687
PATRIC 32122867
EchoBASE EB1496
EcoGene EG11534
eggNOG COG0071
HOGENOM HOG000251750
InParanoid P0C054
KO K04080
OMA MRNYDLT
OrthoDB EOG65TRT6
PhylomeDB P0C054
BioCyc EcoCyc:EG11534-MONOMER
ECOL316407:JW3664-MONOMER
PRO PR:P0C054
Proteomes UP000000318
UP000000625
Genevestigator P0C054
GO GO:0005737
GO:0042802
GO:0009408
Gene3D 2.60.40.790
HAMAP MF_02000
InterPro IPR002068
IPR008978
IPR023728
Pfam PF00011
SUPFAM SSF49764
PROSITE PS01031

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006950

response to stress

PMID:18524928[1]

ECO:0000314

P

Figure 2 shows protein oxidation by Cu2+ is increased in the absence of IbpA/B.

complete

enables

GO:0042802

identical protein binding

PMID:20433838[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0C054

F

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:8349564[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:12071954[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:12055295[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0050821

protein stabilization

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000037492

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000037492

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Matuszewska, E et al. (2008) Escherichia coli heat-shock proteins IbpA/B are involved in resistance to oxidative stress induced by copper. Microbiology (Reading, Engl.) 154 1739-47 PubMed GONUTS page
  2. Ratajczak, E et al. (2010) IbpA the small heat shock protein from Escherichia coli forms fibrils in the absence of its cochaperone IbpB. FEBS Lett. 584 2253-7 PubMed GONUTS page
  3. Chuang, SE & Blattner, FR (1993) Characterization of twenty-six new heat shock genes of Escherichia coli. J. Bacteriol. 175 5242-52 PubMed GONUTS page
  4. Kitagawa, M et al. (2002) Escherichia coli small heat shock proteins, IbpA and IbpB, protect enzymes from inactivation by heat and oxidants. Eur. J. Biochem. 269 2907-17 PubMed GONUTS page
  5. Kuczyńska-Wiśnik, D et al. (2002) The Escherichia coli small heat-shock proteins IbpA and IbpB prevent the aggregation of endogenous proteins denatured in vivo during extreme heat shock. Microbiology (Reading, Engl.) 148 1757-65 PubMed GONUTS page
  6. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page