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ECOLI:HOLC

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) holC
Protein Name(s) DNA polymerase III subunit chi
External Links
UniProt P28905
EMBL L04574
Z14155
U14003
U00096
AP009048
X15130
PIR A46739
RefSeq NP_418680.1
YP_492397.1
PDB 1EM8
3SXU
PDBsum 1EM8
3SXU
ProteinModelPortal P28905
SMR P28905
DIP DIP-9933N
IntAct P28905
MINT MINT-1224072
STRING 511145.b4259
EnsemblBacteria AAC77216
BAE78256
GeneID 12933731
948787
KEGG ecj:Y75_p4142
eco:b4259
PATRIC 32124089
EchoBASE EB1385
EcoGene EG11413
eggNOG COG2927
HOGENOM HOG000263567
InParanoid P28905
KO K02339
OMA WQFEPSA
OrthoDB EOG68H887
BioCyc EcoCyc:EG11413-MONOMER
ECOL316407:JW4216-MONOMER
EvolutionaryTrace P28905
PRO PR:P28905
Proteomes UP000000318
UP000000625
Genevestigator P28905
GO GO:0043847
GO:0003677
GO:0003887
GO:0006260
GO:0032298
Gene3D 3.40.50.10110
InterPro IPR007459
Pfam PF04364
SUPFAM SSF102400

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0043847

DNA polymerase III, clamp loader chi/psi subcomplex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11413
PANTHER:PTN002446156

C

Seeded From UniProt

complete

involved_in

GO:0032298

positive regulation of DNA-dependent DNA replication initiation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11413
PANTHER:PTN002446156

P

Seeded From UniProt

complete

part_of

GO:0043847

DNA polymerase III, clamp loader chi/psi subcomplex

PMID:9722585[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0AGE0

C

Seeded From UniProt

complete

part_of

GO:0043847

DNA polymerase III, clamp loader chi/psi subcomplex

PMID:12888503[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0AGE0

C

Seeded From UniProt

complete

involved_in

GO:0032298

positive regulation of DNA-dependent DNA replication initiation

PMID:9989506[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009314

response to radiation

PMID:27718375[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003887

P

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003887

P

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003887

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007459

F

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007459

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007459

P

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.7

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

enables

GO:0003887

DNA-directed DNA polymerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0239

F

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Glover, BP & McHenry, CS (1998) The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template. J. Biol. Chem. 273 23476-84 PubMed GONUTS page
  3. Witte, G et al. (2003) DNA polymerase III chi subunit ties single-stranded DNA binding protein to the bacterial replication machinery. Nucleic Acids Res. 31 4434-40 PubMed GONUTS page
  4. Yuzhakov, A et al. (1999) Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase. Cell 96 153-63 PubMed GONUTS page
  5. Sargentini, NJ et al. () Screen for genes involved in radiation survival of Escherichia coli and construction of a reference database. Mutat. Res. 793-794 1-14 PubMed GONUTS page