GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:HEMH

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) hemH (synonyms: popA, visA)
Protein Name(s) Ferrochelatase

Heme synthase Protoheme ferro-lyase

External Links
UniProt P23871
EMBL D90259
U82664
U00096
AP009048
PIR B64778
RefSeq NP_415008.1
YP_488766.1
ProteinModelPortal P23871
SMR P23871
IntAct P23871
STRING 511145.b0475
PaxDb P23871
EnsemblBacteria AAC73577
BAE76254
GeneID 12930855
947532
KEGG ecj:Y75_p0462
eco:b0475
PATRIC 32116107
EchoBASE EB0426
EcoGene EG10431
eggNOG COG0276
HOGENOM HOG000060730
InParanoid P23871
KO K01772
OMA TIEEIGM
OrthoDB EOG6XHC5H
PhylomeDB P23871
BioCyc EcoCyc:PROTOHEME-FERROCHELAT-MONOMER
ECOL316407:JW0464-MONOMER
MetaCyc:PROTOHEME-FERROCHELAT-MONOMER
UniPathway UPA00252
PRO PR:P23871
Proteomes UP000000318
UP000000625
Genevestigator P23871
GO GO:0005737
GO:0004325
GO:0046872
GO:0006783
GO:0046501
GO:0009416
HAMAP MF_00323
InterPro IPR001015
IPR019772
PANTHER PTHR11108
Pfam PF00762
TIGRFAMs TIGR00109
PROSITE PS00534

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006783

heme biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10431
MGI:MGI:95513
PANTHER:PTN000121751
RGD:1307556
SGD:S000005702
TAIR:locus:2180642
UniProtKB:O04921
UniProtKB:P9WNE3
UniProtKB:Q8ID58

P

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10431
FB:FBgn0266268
MGI:MGI:95513
PANTHER:PTN000121751
RGD:1307556
SGD:S000005702
TAIR:locus:2180642
UniProtKB:O04921
UniProtKB:P22830
UniProtKB:Q8ID58
ZFIN:ZDB-GENE-000928-1

F

Seeded From UniProt

complete

involved_in

GO:0046501

protoporphyrinogen IX metabolic process

PMID:1397280[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009416

response to light stimulus

PMID:2051480[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009416

response to light stimulus

PMID:1835790[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006783

heme biosynthetic process

PMID:1835790[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006783

heme biosynthetic process

PMID:8458858[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

PMID:8458858[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

PMID:1397280[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

PMID:8458858[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006783

heme biosynthetic process

PMID:387909[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

PMID:8056770[7]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001015
InterPro:IPR019772

F

Seeded From UniProt

complete

involved_in

GO:0006783

heme biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001015
InterPro:IPR019772

P

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.99.1.1

F

Seeded From UniProt

complete

enables

GO:0004325

ferrochelatase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083313

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083313

C

Seeded From UniProt

complete

involved_in

GO:0006779

porphyrin-containing compound biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083313

P

Seeded From UniProt

complete

involved_in

GO:0006783

heme biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083313

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006783

heme biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0350

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006779

porphyrin-containing compound biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0627

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. ↑ 2.0 2.1 Miyamoto, K et al. (1992) Accumulation of protoporphyrin IX in light-sensitive mutants of Escherichia coli. FEBS Lett. 310 246-8 PubMed GONUTS page
  3. ↑ Miyamoto, K et al. (1991) Isolation and characterization of visible light-sensitive mutants of Escherichia coli K12. J. Mol. Biol. 219 393-8 PubMed GONUTS page
  4. ↑ 4.0 4.1 Nakahigashi, K et al. (1991) Photosensitivity of a protoporphyrin-accumulating, light-sensitive mutant (visA) of Escherichia coli K-12. Proc. Natl. Acad. Sci. U.S.A. 88 10520-4 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 Frustaci, JM & O'Brian, MR (1993) The Escherichia coli visA gene encodes ferrochelatase, the final enzyme of the heme biosynthetic pathway. J. Bacteriol. 175 2154-6 PubMed GONUTS page
  6. ↑ McConville, ML & Charles, HP (1979) Isolation of haemin-requiring mutants of Escherichia coli K12. J. Gen. Microbiol. 113 155-64 PubMed GONUTS page
  7. ↑ Miyamoto, K et al. (1994) Overproduction, purification, and characterization of ferrochelatase from Escherichia coli. J. Biochem. 115 545-51 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=ECOLI:HEMH&oldid=5953313"