GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:GLSA1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) glsA1 (ECO:0000255 with HAMAP-Rule:MF_00313) (synonyms: ybaS)
Protein Name(s) Glutaminase 1 (ECO:0000255 with HAMAP-Rule:MF_00313)
External Links
UniProt P77454
EMBL U82664
U00096
AP009048
PIR D64779
RefSeq NP_415018.1
YP_488776.1
PDB 1U60
PDBsum 1U60
ProteinModelPortal P77454
SMR P77454
DIP DIP-11307N
IntAct P77454
STRING 511145.b0485
PaxDb P77454
PRIDE P77454
EnsemblBacteria AAC73587
BAE76264
GeneID 12932991
946187
KEGG ecj:Y75_p0472
eco:b0485
PATRIC 32116129
EchoBASE EB3036
EcoGene EG13247
eggNOG COG2066
HOGENOM HOG000216890
InParanoid P77454
KO K01425
OMA ISKAFVF
OrthoDB EOG6N94BK
PhylomeDB P77454
BioCyc EcoCyc:G6261-MONOMER
ECOL316407:JW0474-MONOMER
MetaCyc:G6261-MONOMER
EvolutionaryTrace P77454
PRO PR:P77454
Proteomes UP000000318
UP000000625
Genevestigator P77454
GO GO:0004359
GO:0006541
GO:0045926
GO:0010447
Gene3D 3.40.710.10
HAMAP MF_00313
InterPro IPR012338
IPR015868
PANTHER PTHR12544
Pfam PF04960
SUPFAM SSF56601
TIGRFAMs TIGR03814

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006543

glutamine catabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13816
MGI:MGI:95752
PANTHER:PTN000283994
UniProtKB:O94925

P

Seeded From UniProt

complete

involved_in

GO:0006537

glutamate biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95752
PANTHER:PTN000283994
UniProtKB:O94925

P

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13247
EcoGene:EG13816
MGI:MGI:95752
PANTHER:PTN000283994
UniProtKB:O94925

F

Seeded From UniProt

complete

involved_in

GO:0045926

negative regulation of growth

PMID:18459799[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

PMID:18459799[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0051289

protein homotetramerization

PMID:18459799[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010447

response to acidic pH

PMID:23337585[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010447

response to acidic pH

PMID:12730179[4]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

PMID:23337585[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

PMID:18459799[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015868

F

Seeded From UniProt

complete

involved_in

GO:0006541

glutamine metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015868

P

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.1.2

F

Seeded From UniProt

complete

enables

GO:0004359

glutaminase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083254

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Brown, G et al. (2008) Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry 47 5724-35 PubMed GONUTS page
  3. 3.0 3.1 Lu, P et al. (2013) L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia. Cell Res. 23 635-44 PubMed GONUTS page
  4. Tucker, DL et al. (2003) Genes of the GadX-GadW regulon in Escherichia coli. J. Bacteriol. 185 3190-201 PubMed GONUTS page