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ECOLI:GLNK
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | glnK (synonyms: ybaI) | |
| Protein Name(s) | Nitrogen regulatory protein P-II 2 | |
| External Links | ||
| UniProt | P0AC55 | |
| EMBL | U40429 S79842 U82664 U00096 AP009048 | |
| PIR | B64775 | |
| RefSeq | NP_414984.1 YP_488742.1 | |
| PDB | 1GNK 2GNK 2NS1 2NUU | |
| PDBsum | 1GNK 2GNK 2NS1 2NUU | |
| ProteinModelPortal | P0AC55 | |
| SMR | P0AC55 | |
| DIP | DIP-35006N | |
| IntAct | P0AC55 | |
| MINT | MINT-1309225 | |
| STRING | 511145.b0450 | |
| SWISS-2DPAGE | P0AC55 | |
| PaxDb | P0AC55 | |
| PRIDE | P0AC55 | |
| EnsemblBacteria | AAC73553 BAE76230 | |
| GeneID | 12934155 945087 | |
| KEGG | ecj:Y75_p0438 eco:b0450 | |
| PATRIC | 32116055 | |
| EchoBASE | EB2108 | |
| EcoGene | EG12191 | |
| eggNOG | COG0347 | |
| HOGENOM | HOG000017847 | |
| InParanoid | P0AC55 | |
| KO | K04752 | |
| OMA | MVEPAIE | |
| OrthoDB | EOG69GZGV | |
| PhylomeDB | P0AC55 | |
| BioCyc | EcoCyc:PROTEIN-PII2 ECOL316407:JW0440-MONOMER MetaCyc:PROTEIN-PII2 | |
| EvolutionaryTrace | P0AC55 | |
| PRO | PR:P0AC55 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AC55 | |
| GO | GO:0030234 GO:0042802 GO:0000166 GO:0045848 GO:0006355 GO:0006351 | |
| Gene3D | 3.30.70.120 | |
| InterPro | IPR002187 IPR011322 IPR015867 IPR017918 IPR002332 | |
| Pfam | PF00543 | |
| PRINTS | PR00340 | |
| SMART | SM00938 | |
| SUPFAM | SSF54913 | |
| PROSITE | PS00638 PS51343 PS00496 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045848 |
positive regulation of nitrogen utilization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050790 |
regulation of catalytic activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0030234 |
P |
Seeded From UniProt |
complete | ||
| GO:0015696 |
ammonium transport |
ECO:0000315 |
P |
Figure 2. shows how glnK binds with AmtB to physically block the exit of ammonia from the cytoplasm. |
complete | |||||
|
involved_in |
GO:0006808 |
regulation of nitrogen utilization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0009399 |
nitrogen fixation |
ECO:0000315 |
P |
Figure 3. indicates that glnK is required to recover from nitrogen starvation. The figure shows the regrowth of E. coli with glnK |
complete | |||||
|
enables |
GO:0030234 |
enzyme regulator activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
- ↑ Burillo, S et al. (2004) Interactions between the nitrogen signal transduction protein PII and N-acetyl glutamate kinase in organisms that perform oxygenic photosynthesis. J. Bacteriol. 186 3346-54 PubMed GONUTS page
- ↑ 3.0 3.1 Blauwkamp, TA & Ninfa, AJ (2002) Physiological role of the GlnK signal transduction protein of Escherichia coli: survival of nitrogen starvation. Mol. Microbiol. 46 203-14 PubMed GONUTS page
- ↑ Boogerd, FC et al. (2011) AmtB-mediated NH3 transport in prokaryotes must be active and as a consequence regulation of transport by GlnK is mandatory to limit futile cycling of NH4(+)/NH3. FEBS Lett. 585 23-8 PubMed GONUTS page
