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ECOLI:GLCA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) glcA (synonyms: yghK)
Protein Name(s) Glycolate permease GlcA
External Links
UniProt Q46839
EMBL U28377
U00096
AP009048
PIR E65083
RefSeq NP_417449.1
YP_491171.1
ProteinModelPortal Q46839
SMR Q46839
DIP DIP-12206N
IntAct Q46839
STRING 511145.b2975
TCDB 2.A.14.1.2
PRIDE Q46839
EnsemblBacteria AAC76011
BAE77035
GeneID 12930414
947259
KEGG ecj:Y75_p2903
eco:b2975
PATRIC 32121364
EchoBASE EB2818
EcoGene EG12995
eggNOG COG1620
HOGENOM HOG000253321
InParanoid Q46839
KO K02550
OMA FAYVANY
OrthoDB EOG6Q8J3Z
PhylomeDB Q46839
BioCyc EcoCyc:B2975-MONOMER
ECOL316407:JW2942-MONOMER
MetaCyc:B2975-MONOMER
PRO PR:Q46839
Proteomes UP000000318
UP000000625
Genevestigator Q46839
GO GO:0005887
GO:0043879
GO:0015129
GO:0015295
GO:0097339
GO:0035873
GO:0015992
InterPro IPR003804
PANTHER PTHR30003:SF0
Pfam PF02652
TIGRFAMs TIGR00795

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043879

glycolate transmembrane transporter activity

PMID:11283302[1]

ECO:0000316

UniProtKB:P33231


F

Figure 3. Dependence of glycolate transport on the presence of the functional GlcA

complete

enables

GO:0015295

solute:proton symporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11961
EcoGene:EG12995
PANTHER:PTN000768163

F

Seeded From UniProt

complete

enables

GO:0015129

lactate transmembrane transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11961
EcoGene:EG12995
PANTHER:PTN000768163

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11961
EcoGene:EG12995
PANTHER:PTN000768163

C

Seeded From UniProt

complete

enables

GO:0015295

solute:proton symporter activity

PMID:11785976[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:11283302[1]

ECO:0000245

automatically integrated combinatorial evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15919996[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:11283302[1]

ECO:0000245

automatically integrated combinatorial evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0035873

lactate transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0015129

P

Seeded From UniProt

complete

involved_in

GO:0035873

lactate transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015129

P

Seeded From UniProt

complete

involved_in

GO:1902600

proton transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015295

P

Seeded From UniProt

complete

involved_in

GO:1902600

proton transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015295

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003804

C

Seeded From UniProt

complete

enables

GO:0015129

lactate transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003804

F

Seeded From UniProt

complete

involved_in

GO:0015727

lactate transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003804

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-KW:KW-0997
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Núñez, MF et al. (2001) The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. Microbiology (Reading, Engl.) 147 1069-77 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Núñez, MF et al. (2002) Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli. Biochem. Biophys. Res. Commun. 290 824-9 PubMed GONUTS page
  4. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page