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ECOLI:GAL1

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) galK (ECO:0000255 with HAMAP-Rule:MF_00246) (synonyms: galA)
Protein Name(s) Galactokinase (ECO:0000255 with HAMAP-Rule:MF_00246)

Galactose kinase (ECO:0000255 with HAMAP-Rule:MF_00246)

External Links
UniProt P0A6T3
EMBL X02306
U00096
AP009048
U13636
PIR B23044
RefSeq NP_415278.1
YP_489030.1
ProteinModelPortal P0A6T3
SMR P0A6T3
IntAct P0A6T3
STRING 511145.b0757
PaxDb P0A6T3
PRIDE P0A6T3
EnsemblBacteria AAC73844
BAA35419
GeneID 12932717
945358
KEGG ecj:Y75_p0730
eco:b0757
PATRIC 32116715
EchoBASE EB0358
EcoGene EG10363
eggNOG COG0153
HOGENOM HOG000241100
InParanoid P0A6T3
KO K00849
OMA TFYVCKA
OrthoDB EOG6DG2SH
PhylomeDB P0A6T3
BioCyc EcoCyc:GALACTOKIN-MONOMER
ECOL316407:JW0740-MONOMER
MetaCyc:GALACTOKIN-MONOMER
SABIO-RK P0A6T3
UniPathway UPA00214
PRO PR:P0A6T3
Proteomes UP000000318
UP000000625
Genevestigator P0A6T3
GO GO:0005737
GO:0005524
GO:0004335
GO:0000287
GO:0033499
Gene3D 3.30.230.10
3.30.70.890
HAMAP MF_00246
InterPro IPR000705
IPR022963
IPR019741
IPR019539
IPR013750
IPR006204
IPR006203
IPR006206
IPR020568
IPR014721
Pfam PF10509
PF08544
PF00288
PIRSF PIRSF000530
PRINTS PR00473
PR00959
SUPFAM SSF54211
SSF55060
TIGRFAMs TIGR00131
PROSITE PS00106
PS00627

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0033499

galactose catabolic process via UDP-galactose

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10363
PANTHER:PTN000048421
SGD:S000000224

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10363
PANTHER:PTN000048421
TAIR:locus:2075730
TAIR:locus:2084344
TAIR:locus:2130105

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10363
PANTHER:PTN000048421
SGD:S000000224
SGD:S000002416
UniProtKB:P51570

C

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10363
MGI:MGI:95730
PANTHER:PTN000048421
RGD:1305375
SGD:S000000224
TAIR:locus:2075730
TAIR:locus:2084344
UniProtKB:P51570
UniProtKB:Q01415

F

Seeded From UniProt

complete

involved_in

GO:0033499

galactose catabolic process via UDP-galactose

PMID:16590575[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:4889465[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

PMID:13390972[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

PMID:13977183[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0033499

galactose catabolic process via UDP-galactose

PMID:13390972[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

PMID:13977183[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

PMID:13977183[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000705
InterPro:IPR022963

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000705
InterPro:IPR006203
InterPro:IPR006204
InterPro:IPR006206

F

Seeded From UniProt

complete

enables

GO:0005534

galactose binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019539

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006206

C

Seeded From UniProt

complete

involved_in

GO:0006012

galactose metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000705
InterPro:IPR022963

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006206

F

Seeded From UniProt

complete

enables

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006206

F

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000705

P

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.6

F

Seeded From UniProt

complete

enables

GO:0004335

galactokinase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000082084

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000082084

C

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000082084

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000082084

F

Seeded From UniProt

complete

involved_in

GO:0006012

galactose metabolic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000082084

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

involved_in

GO:0006012

galactose metabolic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0299
UniPathway:UPA00214

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. ↑ Kalckar, HM et al. (1959) HEREDITARY DEFECTS IN GALACTOSE METABOLISM IN ESCHERICHIA COLI MUTANTS, I. DETERMINATION OF ENZYME ACTIVITIES. Proc. Natl. Acad. Sci. U.S.A. 45 1776-86 PubMed GONUTS page
  3. ↑ Wilson, DB & Hogness, DS (1969) The enzymes of the galactose operon in Escherichia coli. 3. The size and composition of galactokinase. J. Biol. Chem. 244 2137-42 PubMed GONUTS page
  4. ↑ 4.0 4.1 KURAHASHI, K (1957) Enzyme formation in galactose-negative mutants of Escherichia coli. Science 125 114-6 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 SHERMAN, JR & ADLER, J (1963) Galactokinse from Escherichia coli. J. Biol. Chem. 238 873-8 PubMed GONUTS page
  6. ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
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