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ECOLI:FADE

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) fadE (synonyms: yafH)
Protein Name(s) Acyl-coenzyme A dehydrogenase

ACDH

External Links
UniProt Q47146
EMBL U70214
U00096
AP009048
D38582
PIR F64746
RefSeq NP_414756.2
YP_488518.1
ProteinModelPortal Q47146
SMR Q47146
STRING 511145.b0221
PaxDb Q47146
PRIDE Q47146
EnsemblBacteria AAC73325
BAA77891
GeneID 12930776
949007
KEGG ecj:Y75_p0212
eco:b0221
PATRIC 32115557
EchoBASE EB2939
EcoGene EG13145
eggNOG COG1960
HOGENOM HOG000274434
InParanoid Q47146
KO K06445
OMA DLPLLHW
OrthoDB EOG6VF2ZZ
PhylomeDB Q47146
BioCyc EcoCyc:ACYLCOADEHYDROG-MONOMER
ECOL316407:JW5020-MONOMER
MetaCyc:ACYLCOADEHYDROG-MONOMER
UniPathway UPA00659
PRO PR:Q47146
Proteomes UP000000318
UP000000625
Genevestigator Q47146
GO GO:0003995
GO:0050660
GO:0033539
Gene3D 1.10.540.10
2.40.110.10
InterPro IPR006091
IPR009075
IPR013786
IPR009100
IPR015396
Pfam PF00441
PF02770
PF02771
PF09317
SUPFAM SSF47203
SSF56645

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0052890

oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13974
PANTHER:PTN001656759

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13145
PANTHER:PTN001656759
UniProtKB:P9WJA1
UniProtKB:P9WQF7
UniProtKB:P9WQG3

C

Seeded From UniProt

complete

enables

GO:0003995

acyl-CoA dehydrogenase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13145
PANTHER:PTN001330974

F

Seeded From UniProt

complete

involved_in

GO:0033539

fatty acid beta-oxidation using acyl-CoA dehydrogenase

PMID:12057976[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15919996[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003995

acyl-CoA dehydrogenase activity

PMID:12057976[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003995

acyl-CoA dehydrogenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015396

F

Seeded From UniProt

complete

enables

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006091
InterPro:IPR009075
InterPro:IPR009100
InterPro:IPR013786
InterPro:IPR036250
InterPro:IPR037069

F

Seeded From UniProt

complete

involved_in

GO:0033539

fatty acid beta-oxidation using acyl-CoA dehydrogenase

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015396

P

Seeded From UniProt

complete

enables

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013786
InterPro:IPR037069

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006091
InterPro:IPR009075
InterPro:IPR009100
InterPro:IPR013786
InterPro:IPR015396
InterPro:IPR036250
InterPro:IPR037069

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0276

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

involved_in

GO:0006635

fatty acid beta-oxidation

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00659

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 Campbell, JW & Cronan, JE Jr (2002) The enigmatic Escherichia coli fadE gene is yafH. J. Bacteriol. 184 3759-64 PubMed GONUTS page
  3. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page