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ECOLI:FABZ

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) fabZ (synonyms: sefA, yaeA)
Protein Name(s) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase (3R)-hydroxymyristoyl-ACP dehydrase 17 kDa actomyosin component Beta-hydroxyacyl-ACP dehydratase

External Links
UniProt P0A6Q6
EMBL M19334
U00096
AP009048
U70214
PIR D64742
RefSeq NP_414722.1
YP_488482.1
ProteinModelPortal P0A6Q6
SMR P0A6Q6
DIP DIP-31868N
IntAct P0A6Q6
MINT MINT-1218564
STRING 511145.b0180
PaxDb P0A6Q6
PRIDE P0A6Q6
EnsemblBacteria AAC73291
BAA77855
GeneID 12934249
944888
KEGG ecj:Y75_p0176
eco:b0180
PATRIC 32115471
EchoBASE EB1261
EcoGene EG11284
eggNOG COG0764
HOGENOM HOG000277829
InParanoid P0A6Q6
KO K02372
OMA MCARRRE
OrthoDB EOG6JTCGM
PhylomeDB P0A6Q6
BioCyc EcoCyc:FABZ-MONOMER
ECOL316407:JW0175-MONOMER
MetaCyc:FABZ-MONOMER
PRO PR:P0A6Q6
Proteomes UP000000318
UP000000625
Genevestigator P0A6Q6
GO GO:0005737
GO:0008693
GO:0047451
GO:0042802
GO:0006633
GO:0009245
Gene3D 3.10.129.10
HAMAP MF_00406
InterPro IPR013114
IPR010084
IPR029069
Pfam PF07977
SUPFAM SSF54637
TIGRFAMs TIGR01750

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0047451

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity

PMID:8910376[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:7806516[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008693

3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity

PMID:8910376[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

PMID:8910376[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010084

P

Seeded From UniProt

complete

enables

GO:0016836

hydro-lyase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010084

F

Seeded From UniProt

complete

enables

GO:0019171

3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.1.59

F

Seeded From UniProt

complete

enables

GO:0047451

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.1.59

F

Seeded From UniProt

complete

enables

GO:0008659

(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.1.59

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085106

C

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085106

P

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085106

P

Seeded From UniProt

complete

enables

GO:0016836

hydro-lyase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085106

F

Seeded From UniProt

complete

involved_in

GO:0009245

lipid A biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0441

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Heath, RJ & Rock, CO (1996) Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis. J. Biol. Chem. 271 27795-801 PubMed GONUTS page
  2. Mohan, S et al. (1994) An Escherichia coli gene (FabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase. Relation to fabA and suppression of mutations in lipid A biosynthesis. J. Biol. Chem. 269 32896-903 PubMed GONUTS page