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ECOLI:FABD

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) fabD (synonyms: tfpA)
Protein Name(s) Malonyl CoA-acyl carrier protein transacylase

MCT

External Links
UniProt P0AAI9
EMBL M87040
Z11565
U00096
AP009048
M84991
PIR B41856
RefSeq NP_415610.1
WP_000191372.1
PDB 1MLA
2G1H
2G2O
2G2Y
2G2Z
PDBsum 1MLA
2G1H
2G2O
2G2Y
2G2Z
ProteinModelPortal P0AAI9
SMR P0AAI9
BioGrid 4263368
DIP DIP-47923N
IntAct P0AAI9
STRING 316385.ECDH10B_1164
SwissLipids SLP:000001778
SWISS-2DPAGE P0AAI9
EPD P0AAI9
jPOST P0AAI9
PaxDb P0AAI9
PRIDE P0AAI9
EnsemblBacteria AAC74176
BAA35900
GeneID 945766
KEGG ecj:JW1078
eco:b1092
PATRIC fig|1411691.4.peg.1176
EchoBASE EB1293
EcoGene EG11317
eggNOG ENOG4105CJF
COG0331
HOGENOM HOG000036503
InParanoid P0AAI9
KO K00645
PhylomeDB P0AAI9
BioCyc EcoCyc:MALONYL-COA-ACP-TRANSACYL-MONOMER
ECOL316407:JW1078-MONOMER
MetaCyc:MALONYL-COA-ACP-TRANSACYL-MONOMER
UniPathway UPA00094
EvolutionaryTrace P0AAI9
PRO PR:P0AAI9
Proteomes UP000000318
UP000000625
GO GO:0005829
GO:0004314
GO:0006633
Gene3D 3.40.366.10
InterPro IPR001227
IPR014043
IPR016035
IPR024925
IPR004410
IPR016036
IPR020801
Pfam PF00698
PIRSF PIRSF000446
SMART SM00827
SUPFAM SSF52151
SSF55048
TIGRFAMs TIGR00128

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006633

fatty acid biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11317
PANTHER:PTN002448244
UniProtKB:G3XCZ6
UniProtKB:P9WNG5
UniProtKB:Q8IVS2

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11317
PANTHER:PTN000104995
UniProtKB:P9WNG5

C

Seeded From UniProt

complete

enables

GO:0004314

[acyl-carrier-protein] S-malonyltransferase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11317
PANTHER:PTN002448244
SGD:S000005747
UniProtKB:P9WNG5
UniProtKB:Q8IVS2

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

PMID:4584822[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:15911532[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004314

[acyl-carrier-protein] S-malonyltransferase activity

PMID:1314802[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004314

[acyl-carrier-protein] S-malonyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004410

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001227

F

Seeded From UniProt

complete

enables

GO:0016419

S-malonyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.39

F

Seeded From UniProt

complete

enables

GO:0004314

[acyl-carrier-protein] S-malonyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.39

F

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0276

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0275
UniPathway:UPA00094

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Ruch, FE & Vagelos, PR (1973) The isolation and general properties of Escherichia coli malonyl coenzyme A-acyl carrier protein transacylase. J. Biol. Chem. 248 8086-94 PubMed GONUTS page
  3. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  4. Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
  5. Verwoert, II et al. (1992) Cloning, nucleotide sequence, and expression of the Escherichia coli fabD gene, encoding malonyl coenzyme A-acyl carrier protein transacylase. J. Bacteriol. 174 2851-7 PubMed GONUTS page