GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
ECOLI:FABA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | fabA | |
| Protein Name(s) | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA Beta-hydroxydecanoyl thioester dehydrase Trans-2-decenoyl-[acyl-carrier-protein] isomerase | |
| External Links | ||
| UniProt | P0A6Q3 | |
| EMBL | J03186 U00096 AP009048 U37057 U56977 | |
| PIR | A64836 | |
| RefSeq | NP_415474.1 YP_489226.1 | |
| PDB | 1MKA 1MKB 4KEH | |
| PDBsum | 1MKA 1MKB 4KEH | |
| ProteinModelPortal | P0A6Q3 | |
| SMR | P0A6Q3 | |
| DIP | DIP-31864N | |
| IntAct | P0A6Q3 | |
| MINT | MINT-1218658 | |
| STRING | 511145.b0954 | |
| PaxDb | P0A6Q3 | |
| PRIDE | P0A6Q3 | |
| EnsemblBacteria | AAC74040 BAA35712 | |
| GeneID | 12934245 945568 | |
| KEGG | ecj:Y75_p0926 eco:b0954 | |
| PATRIC | 32117127 | |
| EchoBASE | EB0269 | |
| EcoGene | EG10273 | |
| eggNOG | COG0764 | |
| HOGENOM | HOG000277828 | |
| InParanoid | P0A6Q3 | |
| KO | K01716 | |
| OMA | FFDCHFK | |
| OrthoDB | EOG6VB6SH | |
| PhylomeDB | P0A6Q3 | |
| BioCyc | EcoCyc:FABA-MONOMER ECOL316407:JW0937-MONOMER MetaCyc:FABA-MONOMER | |
| BRENDA | 5.3.3.14 | |
| UniPathway | UPA00094 | |
| EvolutionaryTrace | P0A6Q3 | |
| PRO | PR:P0A6Q3 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A6Q3 | |
| GO | GO:0005737 GO:0008693 GO:0047451 GO:0034017 GO:0006633 GO:0008610 | |
| Gene3D | 3.10.129.10 | |
| HAMAP | MF_00405 | |
| InterPro | IPR010083 IPR013114 IPR029069 | |
| Pfam | PF07977 | |
| SUPFAM | SSF54637 | |
| TIGRFAMs | TIGR01749 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0008610 |
lipid biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
EcoliWiki:fadD |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0047451 |
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0034017 |
trans-2-decenoyl-acyl-carrier-protein isomerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008693 |
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008693 |
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008659 |
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0034017 |
trans-2-decenoyl-acyl-carrier-protein isomerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019171 |
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0047451 |
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000085101 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000085101 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0034017 |
trans-2-decenoyl-acyl-carrier-protein isomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000085101 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008693 |
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000085101 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006631 |
fatty acid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0275 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Feng, Y & Cronan, JE (2009) Escherichia coli unsaturated fatty acid synthesis: complex transcription of the fabA gene and in vivo identification of the essential reaction catalyzed by FabB. J. Biol. Chem. 284 29526-35 PubMed GONUTS page
- ↑ 2.0 2.1 Heath, RJ & Rock, CO (1996) Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis. J. Biol. Chem. 271 27795-801 PubMed GONUTS page
- ↑ Guerra, DJ & Browse, JA (1990) Escherichia coli beta-hydroxydecanoyl thioester dehydrase reacts with native C10 acyl-acyl-carrier proteins of plant and bacterial origin. Arch. Biochem. Biophys. 280 336-45 PubMed GONUTS page
- ↑ Cronan, JE Jr & Gelmann, EP (1973) An estimate of the minimum amount of unsaturated fatty acid required for growth of Escherichia coli. J. Biol. Chem. 248 1188-95 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
b
l
o
