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ECOLI:ENTC
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | entC | |
| Protein Name(s) | Isochorismate synthase EntC
Isochorismate mutase | |
| External Links | ||
| UniProt | P0AEJ2 | |
| EMBL | M36700 M24142 U82598 U00096 AP009048 X53274 | |
| PIR | JT0497 | |
| RefSeq | NP_415125.1 YP_488882.1 | |
| PDB | 3HWO | |
| PDBsum | 3HWO | |
| ProteinModelPortal | P0AEJ2 | |
| SMR | P0AEJ2 | |
| DIP | DIP-47970N | |
| IntAct | P0AEJ2 | |
| MINT | MINT-1300552 | |
| STRING | 511145.b0593 | |
| BindingDB | P0AEJ2 | |
| ChEMBL | CHEMBL1075176 | |
| PaxDb | P0AEJ2 | |
| PRIDE | P0AEJ2 | |
| EnsemblBacteria | AAC73694 BAE76348 | |
| GeneID | 12931992 945511 | |
| KEGG | ecj:Y75_p0582 eco:b0593 | |
| PATRIC | 32116362 | |
| EchoBASE | EB0257 | |
| EcoGene | EG10261 | |
| eggNOG | COG1169 | |
| HOGENOM | HOG000028185 | |
| InParanoid | P0AEJ2 | |
| KO | K02361 | |
| OMA | CAEASER | |
| OrthoDB | EOG6PGK1Z | |
| PhylomeDB | P0AEJ2 | |
| BioCyc | EcoCyc:ENTC-MONOMER ECOL316407:JW0585-MONOMER MetaCyc:ENTC-MONOMER | |
| SABIO-RK | P0AEJ2 | |
| UniPathway | UPA00017 | |
| EvolutionaryTrace | P0AEJ2 | |
| PRO | PR:P0AEJ2 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AEJ2 | |
| GO | GO:0008909 GO:0009239 | |
| Gene3D | 3.60.120.10 | |
| InterPro | IPR005801 IPR015890 IPR004561 | |
| PANTHER | PTHR11236:SF3 | |
| Pfam | PF00425 | |
| SUPFAM | SSF56322 | |
| TIGRFAMs | TIGR00543 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009697 |
salicylic acid biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000132898 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008909 |
isochorismate synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10261 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009239 |
enterobactin biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008909 |
isochorismate synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009239 |
enterobactin biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008909 |
isochorismate synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008909 |
isochorismate synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009058 |
biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008909 |
isochorismate synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009239 |
enterobactin biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0259 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Sridharan, S et al. (2010) Crystal structure of Escherichia coli enterobactin-specific isochorismate synthase (EntC) bound to its reaction product isochorismate: implications for the enzyme mechanism and differential activity of chorismate-utilizing enzymes. J. Mol. Biol. 397 290-300 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Dahm, C et al. (1998) The role of isochorismate hydroxymutase genes entC and menF in enterobactin and menaquinone biosynthesis in Escherichia coli. Biochim. Biophys. Acta 1425 377-86 PubMed GONUTS page
- ↑ Tummuru, MK et al. (1989) The in vitro conversion of chorismate to isochorismate catalyzed by the Escherichia coli entC gene product. Evidence that EntA does not contribute to isochorismate synthase activity. J. Biol. Chem. 264 20547-51 PubMed GONUTS page
- ↑ Ozenberger, BA et al. (1989) Nucleotide sequence of Escherichia coli isochorismate synthetase gene entC and evolutionary relationship of isochorismate synthetase and other chorismate-utilizing enzymes. J. Bacteriol. 171 775-83 PubMed GONUTS page
- ↑ Liu, J et al. (1990) Overexpression, purification, and characterization of isochorismate synthase (EntC), the first enzyme involved in the biosynthesis of enterobactin from chorismate. Biochemistry 29 1417-25 PubMed GONUTS page
