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ECOLI:EDD

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) edd
Protein Name(s) Phosphogluconate dehydratase

6-phosphogluconate dehydratase

External Links
UniProt P0ADF6
EMBL M87458
X63694
U00096
AP009048
L20897
PIR A42986
RefSeq NP_416365.1
YP_490113.1
ProteinModelPortal P0ADF6
SMR P0ADF6
DIP DIP-47906N
IntAct P0ADF6
STRING 511145.b1851
PaxDb P0ADF6
PRIDE P0ADF6
EnsemblBacteria AAC74921
BAA15659
GeneID 12932388
946362
KEGG ecj:Y75_p1827
eco:b1851
PATRIC 32119023
EchoBASE EB0253
EcoGene EG10257
eggNOG COG0129
HOGENOM HOG000173157
InParanoid P0ADF6
KO K01690
OMA CQHEVEA
OrthoDB EOG61ZTBF
PhylomeDB P0ADF6
BioCyc EcoCyc:PGLUCONDEHYDRAT-MONOMER
ECOL316407:JW1840-MONOMER
MetaCyc:PGLUCONDEHYDRAT-MONOMER
RETL1328306-WGS:GSTH-715-MONOMER
UniPathway UPA00226
PRO PR:P0ADF6
Proteomes UP000000318
UP000000625
Genevestigator P0ADF6
GO GO:0004456
GO:0009255
InterPro IPR004786
IPR015928
IPR000581
IPR020558
PANTHER PTHR21000
Pfam PF00920
SUPFAM SSF52016
TIGRFAMs TIGR01196
PROSITE PS00886
PS00887

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10496
PANTHER:PTN000470254

C

Seeded From UniProt

complete

enables

GO:0004456

phosphogluconate dehydratase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10257
PANTHER:PTN000470269

F

Seeded From UniProt

complete

enables

GO:0004456

phosphogluconate dehydratase activity

PMID:5337844[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0046177

D-gluconate catabolic process

PMID:5337844[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004456

phosphogluconate dehydratase activity

PMID:1846355[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000581
InterPro:IPR020558

F

Seeded From UniProt

complete

enables

GO:0004456

phosphogluconate dehydratase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004786

F

Seeded From UniProt

complete

involved_in

GO:0009255

Entner-Doudoroff pathway through 6-phosphogluconate

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004786

P

Seeded From UniProt

complete

enables

GO:0004456

phosphogluconate dehydratase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.1.12

F

Seeded From UniProt

complete

involved_in

GO:0019521

D-gluconate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0311

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

involved_in

GO:0009255

Entner-Doudoroff pathway through 6-phosphogluconate

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00226

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 Zablotny, R & Fraenkel, DG (1967) Glucose and gluconate metabolism in a mutant of Escherichia coli lacking gluconate-6-phosphate dehydrase. J. Bacteriol. 93 1579-81 PubMed GONUTS page
  3. Gardner, PR & Fridovich, I (1991) Superoxide sensitivity of the Escherichia coli 6-phosphogluconate dehydratase. J. Biol. Chem. 266 1478-83 PubMed GONUTS page