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ECOLI:DSBB
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | dsbB (synonyms: roxB, ycgA) | |
| Protein Name(s) | Disulfide bond formation protein B
Disulfide oxidoreductase | |
| External Links | ||
| UniProt | P0A6M2 | |
| EMBL | L03721 U00096 AP009048 M83655 | |
| PIR | F64864 | |
| RefSeq | NP_415703.3 YP_489452.1 | |
| PDB | 2HI7 2K73 2K74 2LEG 2LTQ 2ZUP 2ZUQ 3E9J | |
| PDBsum | 2HI7 2K73 2K74 2LEG 2LTQ 2ZUP 2ZUQ 3E9J | |
| ProteinModelPortal | P0A6M2 | |
| SMR | P0A6M2 | |
| IntAct | P0A6M2 | |
| MINT | MINT-6742413 | |
| STRING | 511145.b1185 | |
| BindingDB | P0A6M2 | |
| TCDB | 5.A.2.1.1 | |
| EnsemblBacteria | AAC74269 BAA36032 | |
| GeneID | 12932821 946344 | |
| KEGG | ecj:Y75_p1157 eco:b1185 | |
| PATRIC | 32117616 | |
| EchoBASE | EB1366 | |
| EcoGene | EG11393 | |
| eggNOG | COG1495 | |
| HOGENOM | HOG000218135 | |
| InParanoid | P0A6M2 | |
| KO | K03611 | |
| OMA | PSPFVTC | |
| OrthoDB | EOG6CCH7H | |
| BioCyc | EcoCyc:DSBBPROT-MONOMER ECOL316407:JW5182-MONOMER MetaCyc:DSBBPROT-MONOMER | |
| EvolutionaryTrace | P0A6M2 | |
| PRO | PR:P0A6M2 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A6M2 | |
| GO | GO:0016021 GO:0005886 GO:0009055 GO:0015035 GO:0022900 GO:0009408 | |
| Gene3D | 1.20.1550.10 | |
| HAMAP | MF_00286 | |
| InterPro | IPR003752 IPR022920 IPR023380 | |
| Pfam | PF02600 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003756 |
protein disulfide isomerase activity |
ECO:0000315 |
F |
Fig 4 shows how dsbB/dsbA complex forms a disulfide bond. |
complete | |||||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11393 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002195183 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0022900 |
electron transport chain |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009408 |
response to heat |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000083131 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000083131 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000083131 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0009055 |
electron transfer activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000083131 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Inaba, K et al. (2006) Crystal structure of the DsbB-DsbA complex reveals a mechanism of disulfide bond generation. Cell 127 789-801 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Kadokura, H & Beckwith, J (2002) Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA. EMBO J. 21 2354-63 PubMed GONUTS page
- ↑ 4.0 4.1 Bardwell, JC et al. (1993) A pathway for disulfide bond formation in vivo. Proc. Natl. Acad. Sci. U.S.A. 90 1038-42 PubMed GONUTS page
- ↑ Krisko, A et al. (2014) Inferring gene function from evolutionary change in signatures of translation efficiency. Genome Biol. 15 R44 PubMed GONUTS page
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