GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
ECOLI:DSBA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | dsbA (synonyms: dsf, ppfA) | |
| Protein Name(s) | Thiol:disulfide interchange protein DsbA | |
| External Links | ||
| UniProt | P0AEG4 | |
| EMBL | X80762 M77746 X63186 L19201 U00096 AP009048 U35817 U35818 U35819 U35820 U35821 U35822 U35823 U35824 U35825 U36828 U36829 U36830 U36831 U36832 U36833 U36834 U36835 U35662 | |
| PIR | A39292 | |
| RefSeq | NP_418297.1 YP_491589.1 | |
| PDB | 1A23 1A24 1A2J 1A2L 1A2M 1AC1 1ACV 1BQ7 1DSB 1FVJ 1FVK 1TI1 1U3A 1UN2 2B3S 2B6M 2HI7 2LEG 2ZUP 3E9J | |
| PDBsum | 1A23 1A24 1A2J 1A2L 1A2M 1AC1 1ACV 1BQ7 1DSB 1FVJ 1FVK 1TI1 1U3A 1UN2 2B3S 2B6M 2HI7 2LEG 2ZUP 3E9J | |
| ProteinModelPortal | P0AEG4 | |
| SMR | P0AEG4 | |
| DIP | DIP-35886N | |
| IntAct | P0AEG4 | |
| MINT | MINT-1247943 | |
| STRING | 511145.b3860 | |
| SWISS-2DPAGE | P0AEG4 | |
| PaxDb | P0AEG4 | |
| PRIDE | P0AEG4 | |
| EnsemblBacteria | AAC76858 BAE77448 | |
| GeneID | 12932206 948353 | |
| KEGG | ecj:Y75_p3325 eco:b3860 | |
| PATRIC | 32123217 | |
| EchoBASE | EB1274 | |
| EcoGene | EG11297 | |
| eggNOG | COG0526 | |
| HOGENOM | HOG000265316 | |
| InParanoid | P0AEG4 | |
| KO | K03673 | |
| OMA | QVMEFFS | |
| OrthoDB | EOG68Q0Q6 | |
| PhylomeDB | P0AEG4 | |
| BioCyc | EcoCyc:DISULFOXRED-MONOMER ECOL316407:JW3832-MONOMER MetaCyc:DISULFOXRED-MONOMER | |
| EvolutionaryTrace | P0AEG4 | |
| PRO | PR:P0AEG4 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AEG4 | |
| GO | GO:0030288 GO:0003756 GO:0015035 GO:0045454 GO:0071236 GO:0055114 GO:0006457 | |
| Gene3D | 3.40.30.10 | |
| InterPro | IPR001853 IPR023205 IPR012336 IPR017937 | |
| Pfam | PF01323 | |
| PIRSF | PIRSF001488 | |
| SUPFAM | SSF52833 | |
| PROSITE | PS00194 PS51352 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006467 |
protein thiol-disulfide exchange |
ECO:0000315 |
P |
In dsbA mutant cells, pulse-labeled beta-lactamase, alkaline phosphatase, and OmpA are secreted but largely lack disulfide bonds. |
complete | |||||
|
involved_in |
GO:0071236 |
cellular response to antibiotic |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030288 |
outer membrane-bounded periplasmic space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030288 |
outer membrane-bounded periplasmic space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030288 |
outer membrane-bounded periplasmic space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0015035 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015035 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015035 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015035 |
protein disulfide oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045454 |
cell redox homeostasis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042597 |
periplasmic space |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Bardwell, JC et al. (1991) Identification of a protein required for disulfide bond formation in vivo. Cell 67 581-9 PubMed GONUTS page
- ↑ Missiakas, D et al. (1995) Identification and characterization of a new disulfide isomerase-like protein (DsbD) in Escherichia coli. EMBO J. 14 3415-24 PubMed GONUTS page
- ↑ Metheringham, R et al. (1995) An essential role for DsbA in cytochrome c synthesis and formate-dependent nitrite reduction by Escherichia coli K-12. Arch. Microbiol. 164 301-7 PubMed GONUTS page
- ↑ Han, MJ et al. (2014) Comparison of the large-scale periplasmic proteomes of the Escherichia coli K-12 and B strains. J. Biosci. Bioeng. 117 437-42 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
