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ECOLI:DOSP
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | dosP (synonyms: dos, yddU) | |
| Protein Name(s) | Oxygen sensor protein DosP
Direct oxygen-sensing phosphodiesterase Direct oxygen sensor protein Ec DOS Heme-regulated cyclic di-GMP phosphodiesterase, | |
| External Links | ||
| UniProt | P76129 | |
| EMBL | U00096 AP009048 | |
| PIR | D64902 | |
| RefSeq | NP_416006.4 YP_489754.1 | |
| PDB | 1S66 1S67 1V9Y 1V9Z 1VB6 4HU3 4HU4 | |
| PDBsum | 1S66 1S67 1V9Y 1V9Z 1VB6 4HU3 4HU4 | |
| ProteinModelPortal | P76129 | |
| SMR | P76129 | |
| IntAct | P76129 | |
| STRING | 511145.b1489 | |
| EnsemblBacteria | AAC74562 BAA15154 | |
| GeneID | 12930425 945815 | |
| KEGG | ecj:Y75_p1465 eco:b1489 | |
| PATRIC | 32118272 | |
| EchoBASE | EB3553 | |
| EcoGene | EG13792 | |
| eggNOG | COG2202 | |
| HOGENOM | HOG000136246 | |
| InParanoid | P76129 | |
| KO | K13243 | |
| OMA | CHEVERI | |
| OrthoDB | EOG69GZGV | |
| PhylomeDB | P76129 | |
| BioCyc | EcoCyc:G6783-MONOMER ECOL316407:JW1484-MONOMER MetaCyc:G6783-MONOMER | |
| SABIO-RK | P76129 | |
| EvolutionaryTrace | P76129 | |
| PRO | PR:P76129 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P76129 | |
| GO | GO:0071111 GO:0020037 GO:0000287 GO:0019826 GO:0000155 GO:0006355 GO:0006351 | |
| Gene3D | 3.20.20.450 | |
| InterPro | IPR012226 IPR001633 IPR000160 IPR029787 IPR001610 IPR000014 IPR000700 | |
| Pfam | PF00563 PF00990 PF13426 | |
| PIRSF | PIRSF005925 | |
| SMART | SM00052 SM00267 SM00086 SM00091 | |
| SUPFAM | SSF141868 SSF55073 SSF55785 | |
| TIGRFAMs | TIGR00254 TIGR00229 | |
| PROSITE | PS50883 PS50887 PS50113 PS50112 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0019826 |
oxygen sensor activity |
ECO:0000314 |
F |
Figure 4 |
complete | |||||
|
enables |
GO:0019826 |
oxygen sensor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0071111 |
cyclic-guanylate-specific phosphodiesterase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070482 |
response to oxygen levels |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0020037 |
heme binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0071111 |
cyclic-guanylate-specific phosphodiesterase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050896 |
response to stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Tuckerman, JR et al. (2009) An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control. Biochemistry 48 9764-74 PubMed GONUTS page
- ↑ Schmidt, AJ et al. (2005) The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains. J. Bacteriol. 187 4774-81 PubMed GONUTS page
- ↑ Yoshimura-Suzuki, T et al. (2005) DOS(Ec), a heme-regulated phosphodiesterase, plays an important role in the regulation of the cyclic AMP level in Escherichia coli. J. Bacteriol. 187 6678-82 PubMed GONUTS page
- ↑ Delgado-Nixon, VM et al. (2000) Dos, a heme-binding PAS protein from Escherichia coli, is a direct oxygen sensor. Biochemistry 39 2685-91 PubMed GONUTS page
- ↑ Yoshimura, T et al. (2003) Relationships between heme incorporation, tetramer formation, and catalysis of a heme-regulated phosphodiesterase from Escherichia coli: a study of deletion and site-directed mutants. J. Biol. Chem. 278 53105-11 PubMed GONUTS page
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