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ECOLI:DMLA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | dmlA (synonyms: yeaU) | |
| Protein Name(s) | D-malate dehydrogenase [decarboxylating]
D-malate degradation protein A D-malate oxidase | |
| External Links | ||
| UniProt | P76251 | |
| EMBL | U00096 AP009048 | |
| PIR | H64940 | |
| RefSeq | NP_416314.1 YP_490061.1 | |
| ProteinModelPortal | P76251 | |
| SMR | P76251 | |
| DIP | DIP-11800N | |
| IntAct | P76251 | |
| MINT | MINT-1273575 | |
| STRING | 511145.b1800 | |
| PaxDb | P76251 | |
| PRIDE | P76251 | |
| EnsemblBacteria | AAC74870 BAA15595 | |
| GeneID | 12931341 946319 | |
| KEGG | ecj:Y75_p1775 eco:b1800 | |
| PATRIC | 32118917 | |
| EchoBASE | EB3280 | |
| EcoGene | EG13507 | |
| eggNOG | COG0473 | |
| HOGENOM | HOG000021111 | |
| InParanoid | P76251 | |
| KO | K07246 | |
| OMA | CEYYAHH | |
| OrthoDB | EOG65N1BN | |
| PhylomeDB | P76251 | |
| BioCyc | EcoCyc:G6986-MONOMER ECOL316407:JW1789-MONOMER MetaCyc:G6986-MONOMER | |
| PRO | PR:P76251 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P76251 | |
| GO | GO:0005737 GO:0046553 GO:0000287 GO:0051287 GO:0006108 | |
| Gene3D | 3.40.718.10 | |
| InterPro | IPR019818 IPR001804 IPR024084 IPR011829 | |
| PANTHER | PTHR11835 | |
| Pfam | PF00180 | |
| TIGRFAMs | TIGR02089 | |
| PROSITE | PS00470 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0046553 |
D-malate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
F |
Figure 2 (C) yeaU (dmlA) showed increase expression levels during growth on D-malate compared to growth on L-lactate providing evidence for its involvement in D-malate catabolism. |
complete | |||||
|
enables |
GO:0046553 |
D-malate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
NOT|enables |
GO:0009027 |
tartrate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006108 |
malate metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046553 |
D-malate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046553 |
D-malate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009027 |
tartrate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006108 |
malate metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003862 |
3-isopropylmalate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046553 |
D-malate dehydrogenase (decarboxylating) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Reed, JL et al. (2006) Systems approach to refining genome annotation. Proc. Natl. Acad. Sci. U.S.A. 103 17480-4 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Lukas, H et al. (2010) Regulation of aerobic and anaerobic D-malate metabolism of Escherichia coli by the LysR-type regulator DmlR (YeaT). J. Bacteriol. 192 2503-11 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Vorobieva, AA et al. (2014) Escherichia coli D-malate dehydrogenase, a generalist enzyme active in the leucine biosynthesis pathway. J. Biol. Chem. 289 29086-96 PubMed GONUTS page
