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ECOLI:DHE4

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) gdhA
Protein Name(s) NADP-specific glutamate dehydrogenase

NADP-GDH

External Links
UniProt P00370
EMBL J01615
K02499
U00096
AP009048
PIR A00382
RefSeq NP_416275.1
YP_490022.1
PDB 2YFH
3SBO
4BHT
PDBsum 2YFH
3SBO
4BHT
ProteinModelPortal P00370
SMR P00370
DIP DIP-9756N
IntAct P00370
STRING 511145.b1761
SWISS-2DPAGE P00370
PaxDb P00370
PRIDE P00370
EnsemblBacteria AAC74831
BAA15550
GeneID 12931328
946802
KEGG ecj:Y75_p1736
eco:b1761
PATRIC 32118833
EchoBASE EB0367
EcoGene EG10372
eggNOG COG0334
HOGENOM HOG000243799
InParanoid P00370
KO K00262
OMA KGKSEHE
OrthoDB EOG65XN4D
PhylomeDB P00370
BioCyc EcoCyc:GDHA-MONOMER
ECOL316407:JW1750-MONOMER
MetaCyc:GDHA-MONOMER
PRO PR:P00370
Proteomes UP000000318
UP000000625
Genevestigator P00370
GO GO:0005737
GO:0004354
GO:0006537
Gene3D 3.40.50.720
InterPro IPR006095
IPR006096
IPR006097
IPR014362
IPR016040
Pfam PF00208
PF02812
PIRSF PIRSF000185
PRINTS PR00082
SMART SM00839
PROSITE PS00074

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006537

glutamate biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10372
PANTHER:PTN000176341
SGD:S000000058
SGD:S000005902
UniProtKB:Q8ILF7

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10372
PANTHER:PTN000176341
UniProtKB:P18819
UniProtKB:Q8ILT0

C

Seeded From UniProt

complete

enables

GO:0004354

glutamate dehydrogenase (NADP+) activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10372
PANTHER:PTN000176341
PomBase:SPCC622.12c
SGD:S000000058
SGD:S000005902
UniProtKB:P18819
UniProtKB:Q8ILF7
UniProtKB:Q8ILT0

F

Seeded From UniProt

complete

involved_in

GO:0006537

glutamate biosynthetic process

PMID:241744[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:241744[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004354

glutamate dehydrogenase (NADP+) activity

PMID:241744[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:241744[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P00370

F

Seeded From UniProt

complete

involved_in

GO:0006537

glutamate biosynthetic process

PMID:241744[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:15911532[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004354

glutamate dehydrogenase (NADP+) activity

PMID:241744[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006520

cellular amino acid metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006095
InterPro:IPR006096
InterPro:IPR006097

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006095
InterPro:IPR006096
InterPro:IPR006097

F

Seeded From UniProt

complete

enables

GO:0016639

oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014362
InterPro:IPR033922

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006095
InterPro:IPR006096
InterPro:IPR006097
InterPro:IPR014362

P

Seeded From UniProt

complete

enables

GO:0004354

glutamate dehydrogenase (NADP+) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.4.1.4

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Sakamoto, N et al. (1975) Glutamate dehydrogenase from Escherichia coli: purification and properties. J. Bacteriol. 124 775-83 PubMed GONUTS page
  3. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  4. Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page