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ECOLI:DADA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | dadA (synonyms: dadR) | |
| Protein Name(s) | D-amino acid dehydrogenase
D-alanine dehydrogenase | |
| External Links | ||
| UniProt | P0A6J5 | |
| EMBL | L02948 U00096 AP009048 | |
| PIR | B53383 | |
| RefSeq | NP_415707.1 YP_489456.1 | |
| ProteinModelPortal | P0A6J5 | |
| SMR | P0A6J5 | |
| DIP | DIP-6852N | |
| IntAct | P0A6J5 | |
| STRING | 511145.b1189 | |
| PaxDb | P0A6J5 | |
| PRIDE | P0A6J5 | |
| EnsemblBacteria | AAC74273 BAA36044 | |
| GeneID | 12931110 945752 | |
| KEGG | ecj:Y75_p1161 eco:b1189 | |
| PATRIC | 32117624 | |
| EchoBASE | EB1379 | |
| EcoGene | EG11407 | |
| eggNOG | COG0665 | |
| HOGENOM | HOG000217450 | |
| InParanoid | P0A6J5 | |
| KO | K00285 | |
| OMA | DAYVMAC | |
| OrthoDB | EOG6KMBD9 | |
| PhylomeDB | P0A6J5 | |
| BioCyc | EcoCyc:DALADEHYDROGA-MONOMER ECOL316407:JW1178-MONOMER MetaCyc:DALADEHYDROGA-MONOMER | |
| UniPathway | UPA00043 | |
| PRO | PR:P0A6J5 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A6J5 | |
| GO | GO:0005886 GO:0008718 GO:0055130 GO:0019480 | |
| Gene3D | 3.40.50.720 | |
| HAMAP | MF_01202 | |
| InterPro | IPR023080 IPR006076 IPR016040 | |
| Pfam | PF01266 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016491 |
oxidoreductase activity |
PMID:PMC3130732 |
ECO:0000315 |
F |
Figure 4 shows that the inability of the ΔhinT mutant to grow on D-alanine was due to a lack of DadA enzyme activity. |
complete | ||||
|
involved_in |
GO:0055130 |
D-alanine catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11407 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11822 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008718 |
D-amino-acid dehydrogenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11407 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11407 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000354057 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055130 |
D-alanine catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019480 |
L-alanine oxidation to pyruvate via D-alanine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019480 |
L-alanine oxidation to pyruvate via D-alanine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008718 |
D-amino-acid dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008718 |
D-amino-acid dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008718 |
D-amino-acid dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019478 |
D-amino acid catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019478 |
D-amino acid catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100955 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008718 |
D-amino-acid dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100955 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0997 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055130 |
D-alanine catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00043 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 Wild, J & Klopotowski, T (1981) D-Amino acid dehydrogenase of Escherichia coli K12: positive selection of mutants defective in enzyme activity and localization of the structural gene. Mol. Gen. Genet. 181 373-8 PubMed GONUTS page
- ↑ Beelen, RH et al. (1973) A regulatory gene and a structural gene for alaninase in Escherichia coli. Mol. Gen. Genet. 121 369-74 PubMed GONUTS page
- ↑ Jones, H & Venables, WA (1983) Effects of solubilisation on some properties of the membrane-bound respiratory enzyme D-amino acid dehydrogenase of Escherichia coli. FEBS Lett. 151 189-92 PubMed GONUTS page
- ↑ 5.0 5.1 Franklin, FC & Venables, WA (1976) Biochemical, genetic, and regulatory studies of alanine catabolism in Escherichia coli K12. Mol. Gen. Genet. 149 229-37 PubMed GONUTS page
- ↑ Jones, H & Venables, WA (1983) Solubilisation of D-amino acid dehydrogenase of Escherichia coli K12 and its re-binding to envelope preparations. Biochimie 65 177-83 PubMed GONUTS page
