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ECOLI:CYSJ
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | cysJ (ECO:0000255 with HAMAP-Rule:MF_01541) | |
| Protein Name(s) | Sulfite reductase [NADPH] flavoprotein alpha-component (ECO:0000255 with HAMAP-Rule:MF_01541)
SiR-FP (ECO:0000255 with HAMAP-Rule:MF_01541) | |
| External Links | ||
| UniProt | P38038 | |
| EMBL | M23008 U29579 U00096 AP009048 | |
| PIR | H65057 | |
| RefSeq | NP_417244.1 WP_000211913.1 | |
| PDB | 1DDG 1DDI 1YKG | |
| PDBsum | 1DDG 1DDI 1YKG | |
| DisProt | DP00190 | |
| ProteinModelPortal | P38038 | |
| SMR | P38038 | |
| BioGrid | 4262283 | |
| DIP | DIP-9381N | |
| IntAct | P38038 | |
| MINT | MINT-1239442 | |
| STRING | 511145.b2764 | |
| DrugBank | DB03147 | |
| EPD | P38038 | |
| PaxDb | P38038 | |
| EnsemblBacteria | AAC75806 BAE76841 | |
| GeneID | 947239 | |
| KEGG | ecj:JW2734 eco:b2764 | |
| PATRIC | 32120940 | |
| EchoBASE | EB0188 | |
| EcoGene | EG10191 | |
| eggNOG | ENOG4107EER COG0369 | |
| HOGENOM | HOG000282025 | |
| InParanoid | P38038 | |
| KO | K00380 | |
| OMA | GVWYEND | |
| OrthoDB | EOG6CVV7G | |
| PhylomeDB | P38038 | |
| BioCyc | EcoCyc:ALPHACOMP-MONOMER ECOL316407:JW2734-MONOMER MetaCyc:ALPHACOMP-MONOMER | |
| BRENDA | 1.8.1.2 | |
| UniPathway | UPA00140 | |
| EvolutionaryTrace | P38038 | |
| PRO | PR:P38038 | |
| Proteomes | UP000000318 UP000000625 | |
| GO | GO:0009337 GO:0050660 GO:0010181 GO:0005506 GO:0042602 GO:0004783 GO:0019344 GO:0070814 GO:0000103 | |
| Gene3D | 1.20.990.10 3.40.50.360 | |
| HAMAP | MF_01541 | |
| InterPro | IPR010199 IPR029758 IPR003097 IPR017927 IPR001094 IPR008254 IPR001709 IPR029039 IPR023173 IPR001433 IPR017938 | |
| Pfam | PF00667 PF00258 PF00175 | |
| PIRSF | PIRSF000207 | |
| PRINTS | PR00369 PR00371 | |
| SUPFAM | SSF52218 SSF63380 | |
| TIGRFAMs | TIGR01931 | |
| PROSITE | PS51384 PS50902 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009055 |
electron carrier activity |
other:GO_REF:0000100 |
ECO:0000247 |
|
F |
The transfer annotation HHpred hits had an E-value of 1.7E-28, a similarity of 100%, and a query coverage of 94.12% which serves as the evidence. |
complete | |||
|
enables |
GO:0070401 |
NADP+ binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10191 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97744 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0010181 |
FMN binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10191 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000453956 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042602 |
riboflavin reductase (NADPH) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0010181 |
FMN binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009337 |
sulfite reductase complex (NADPH) |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000103 |
sulfate assimilation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004783 |
sulfite reductase (NADPH) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0010181 |
FMN binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001094 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001433 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019344 |
cysteine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001094 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004783 |
sulfite reductase (NADPH) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004783 |
sulfite reductase (NADPH) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000079062 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070814 |
hydrogen sulfide biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000079062 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000103 |
sulfate assimilation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000079062 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019344 |
cysteine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070814 |
hydrogen sulfide biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00140 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Helms, LR et al. (1990) Identification, sequence determination, and expression of the flavodoxin gene from Desulfovibrio salexigens. Biochem. Biophys. Res. Commun. 168 809-17 PubMed GONUTS page
- ↑ 2.0 2.1 Gruez, A et al. (2000) Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module. J. Mol. Biol. 299 199-212 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Eschenbrenner, M et al. (1995) The flavin reductase activity of the flavoprotein component of sulfite reductase from Escherichia coli. A new model for the protein structure. J. Biol. Chem. 270 20550-5 PubMed GONUTS page
- ↑ Covès, J et al. (1993) NADPH-sulfite reductase from Escherichia coli. A flavin reductase participating in the generation of the free radical of ribonucleotide reductase. J. Biol. Chem. 268 18604-9 PubMed GONUTS page