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ECOLI:CSRA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | csrA (synonyms: zfiA) | |
| Protein Name(s) | Carbon storage regulator | |
| External Links | ||
| UniProt | P69913 | |
| EMBL | L07596 D44453 U00096 AP009048 | |
| PIR | B40608 | |
| RefSeq | NP_417176.1 YP_490905.1 | |
| PDB | 1Y00 | |
| PDBsum | 1Y00 | |
| ProteinModelPortal | P69913 | |
| SMR | P69913 | |
| DIP | DIP-47836N | |
| IntAct | P69913 | |
| MINT | MINT-1317679 | |
| STRING | 511145.b2696 | |
| PaxDb | P69913 | |
| PRIDE | P69913 | |
| EnsemblBacteria | AAC75738 BAA16558 | |
| GeneID | 12930427 947176 | |
| KEGG | ecj:Y75_p2634 eco:b2696 | |
| PATRIC | 32120786 | |
| EchoBASE | EB1416 | |
| EcoGene | EG11447 | |
| eggNOG | COG1551 | |
| HOGENOM | HOG000020767 | |
| InParanoid | P69913 | |
| KO | K03563 | |
| OMA | KDIAVHR | |
| OrthoDB | EOG6DC6PM | |
| PhylomeDB | P69913 | |
| BioCyc | EcoCyc:EG11447-MONOMER ECOL316407:JW2666-MONOMER | |
| EvolutionaryTrace | P69913 | |
| PRO | PR:P69913 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P69913 | |
| GO | GO:0048027 GO:0006402 GO:0045719 GO:0045947 | |
| HAMAP | MF_00167 | |
| InterPro | IPR003751 | |
| Pfam | PF02599 | |
| ProDom | PD009007 | |
| TIGRFAMs | TIGR00202 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0017148 |
negative regulation of translation |
ECO:0000315 |
P |
Figure 6 |
complete | |||||
| GO:0048255 |
mRNA stabilization |
ECO:0000315 |
P |
Figure 6, mRNA half-life reduced in csrA mutant compared to WT |
complete | |||||
| GO:0031438 |
negative regulation of mRNA cleavage |
ECO:0000314 |
P |
Figure 5A, in vitro experiment using purified RNase E. In the presence of CsrA, the RNA was protected from RNase E cleavage. |
complete | |||||
|
enables |
GO:0048027 |
mRNA 5'-UTR binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11447 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045947 |
negative regulation of translational initiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11447 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11447 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0048027 |
mRNA 5'-UTR binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0048027 |
mRNA 5'-UTR binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045947 |
negative regulation of translational initiation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045719 |
negative regulation of glycogen biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006109 |
regulation of carbohydrate metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006402 |
mRNA catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000009905 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045948 |
positive regulation of translational initiation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000009905 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006109 |
regulation of carbohydrate metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000009905 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0048027 |
mRNA 5'-UTR binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000009905 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045947 |
negative regulation of translational initiation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000009905 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006417 |
regulation of translation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Baker, CS et al. (2007) CsrA inhibits translation initiation of Escherichia coli hfq by binding to a single site overlapping the Shine-Dalgarno sequence. J. Bacteriol. 189 5472-81 PubMed GONUTS page
- ↑ 2.0 2.1 Yakhnin, AV et al. (2013) CsrA activates flhDC expression by protecting flhDC mRNA from RNase E-mediated cleavage. Mol. Microbiol. 87 851-66 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 Pannuri, A et al. (2012) Translational repression of NhaR, a novel pathway for multi-tier regulation of biofilm circuitry by CsrA. J. Bacteriol. 194 79-89 PubMed GONUTS page
- ↑ 5.0 5.1 Baker, CS et al. (2002) CsrA regulates glycogen biosynthesis by preventing translation of glgC in Escherichia coli. Mol. Microbiol. 44 1599-610 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
