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ECOLI:CSPA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) cspA (synonyms: cspS)
Protein Name(s) Cold shock protein CspA

CSP-A 7.4 kDa cold shock protein CS7.4

External Links
UniProt P0A9X9
EMBL M30139
U00039
U00096
AP009048
U60035
PIR JH0201
RefSeq NP_418012.1
YP_491880.1
PDB 1MJC
2BH8
3MEF
PDBsum 1MJC
2BH8
3MEF
ProteinModelPortal P0A9X9
SMR P0A9X9
DIP DIP-31862N
IntAct P0A9X9
MINT MINT-1220153
STRING 511145.b3556
PaxDb P0A9X9
PRIDE P0A9X9
EnsemblBacteria AAC76580
BAE77739
GeneID 12933539
948070
KEGG ecj:Y75_p3621
eco:b3556
PATRIC 32122584
EchoBASE EB0164
EcoGene EG10166
eggNOG COG1278
HOGENOM HOG000070674
InParanoid P0A9X9
KO K03704
OMA SVTFDVQ
OrthoDB EOG618R0J
PhylomeDB P0A9X9
BioCyc EcoCyc:PD03695
ECOL316407:JW3525-MONOMER
EvolutionaryTrace P0A9X9
PRO PR:P0A9X9
Proteomes UP000000318
UP000000625
Genevestigator P0A9X9
GO GO:0005737
GO:0003677
GO:0003723
GO:0001072
GO:0003697
GO:0003727
GO:0060567
GO:0009409
GO:0031564
GO:0006351
Gene3D 2.40.50.140
InterPro IPR019844
IPR012156
IPR011129
IPR002059
IPR012340
Pfam PF00313
PIRSF PIRSF002599
PRINTS PR00050
SMART SM00357
SUPFAM SSF50249
PROSITE PS00352

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0060567

negative regulation of DNA-templated transcription, termination

PMID:10884409[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009409

response to cold

PMID:3553157[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003727

single-stranded RNA binding

PMID:8995247[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:8995247[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

PMID:8995247[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:7748932[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001072

transcription antitermination factor activity, RNA binding

PMID:10884409[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:8995247[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:1961761[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:3553157[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0031564

transcription antitermination

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0001072

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002059
InterPro:IPR011129
InterPro:IPR012156

F

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:7748932[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bae, W et al. (2000) Escherichia coli CspA-family RNA chaperones are transcription antiterminators. Proc. Natl. Acad. Sci. U.S.A. 97 7784-9 PubMed GONUTS page
  2. 2.0 2.1 Jones, PG et al. (1987) Induction of proteins in response to low temperature in Escherichia coli. J. Bacteriol. 169 2092-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Jiang, W et al. (1997) CspA, the major cold-shock protein of Escherichia coli, is an RNA chaperone. J. Biol. Chem. 272 196-202 PubMed GONUTS page
  4. 4.0 4.1 Brandi, A et al. (1994) Interaction of the main cold shock protein CS7.4 (CspA) of Escherichia coli with the promoter region of hns. Biochimie 76 1090-8 PubMed GONUTS page
  5. La Teana, A et al. (1991) Identification of a cold shock transcriptional enhancer of the Escherichia coli gene encoding nucleoid protein H-NS. Proc. Natl. Acad. Sci. U.S.A. 88 10907-11 PubMed GONUTS page
  6. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page