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ECOLI:CSGA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) csgA
Protein Name(s) Major curlin subunit
External Links
UniProt P28307
EMBL L04979
X90754
U00096
AP009048
PIR S70788
RefSeq NP_415560.1
YP_489309.1
ProteinModelPortal P28307
DIP DIP-9325N
STRING 511145.b1042
EnsemblBacteria AAC74126
BAA35832
GeneID 12931071
949055
KEGG ecj:Y75_p1011
eco:b1042
PATRIC 32117321
EchoBASE EB1452
EcoGene EG11489
eggNOG NOG11590
HOGENOM HOG000118951
InParanoid P28307
KO K04334
OMA SVTQVGF
OrthoDB EOG69SKB1
PhylomeDB P28307
BioCyc EcoCyc:EG11489-MONOMER
ECOL316407:JW1025-MONOMER
PRO PR:P28307
Proteomes UP000000318
UP000000625
Genevestigator P28307
GO GO:0009289
GO:1990000
GO:0007155
GO:0044010
InterPro IPR009742
Pfam PF07012

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042802

identical protein binding

PMID:19966296[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P28307

F

Seeded From UniProt

complete

part_of

GO:0009289

pilus

PMID:11823641[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

PMID:8817489[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1990000

amyloid fibril formation

PMID:19574225[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0044010

single-species biofilm formation

PMID:16172544[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009742

P

Seeded From UniProt

complete

part_of

GO:0009289

pilus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009742

C

Seeded From UniProt

complete

part_of

GO:0009289

pilus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0281
UniProtKB-SubCell:SL-0113

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wang, X et al. (2010) Gatekeeper residues in the major curlin subunit modulate bacterial amyloid fiber biogenesis. Proc. Natl. Acad. Sci. U.S.A. 107 163-8 PubMed GONUTS page
  2. Chapman, MR et al. (2002) Role of Escherichia coli curli operons in directing amyloid fiber formation. Science 295 851-5 PubMed GONUTS page
  3. Hammar, M et al. (1995) Expression of two csg operons is required for production of fibronectin- and congo red-binding curli polymers in Escherichia coli K-12. Mol. Microbiol. 18 661-70 PubMed GONUTS page
  4. Shewmaker, F et al. (2009) The functional curli amyloid is not based on in-register parallel beta-sheet structure. J. Biol. Chem. 284 25065-76 PubMed GONUTS page
  5. Kikuchi, T et al. (2005) Curli fibers are required for development of biofilm architecture in Escherichia coli K-12 and enhance bacterial adherence to human uroepithelial cells. Microbiol. Immunol. 49 875-84 PubMed GONUTS page