ECOLI:CPXR

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	cpxR (synonyms: yiiA)
Protein Name(s)	Transcriptional regulatory protein CpxR
External Links
UniProt	P0AE88
EMBL	L14579 L19201 U00096 AP009048 X13307 M36795
PIR	C65197
RefSeq	NP_418348.1 YP_491538.1
ProteinModelPortal	P0AE88
SMR	P0AE88
DIP	DIP-47991N
IntAct	P0AE88
MINT	MINT-1292432
STRING	511145.b3912
PaxDb	P0AE88
EnsemblBacteria	AAC76894 BAE77397
GeneID	12933651 948404
KEGG	ecj:Y75_p3274 eco:b3912
PATRIC	32123337
EchoBASE	EB0019
EcoGene	EG10020
eggNOG	COG0745
HOGENOM	HOG000034819
InParanoid	P0AE88
KO	K07662
OMA	LSMIGYQ
OrthoDB	EOG6G4VQG
PhylomeDB	P0AE88
BioCyc	EcoCyc:CPXR-MONOMER ECOL316407:JW3883-MONOMER RETL1328306-WGS:GSTH-6652-MONOMER
PRO	PR:P0AE88
Proteomes	UP000000318 UP000000625
Genevestigator	P0AE88
GO	GO:0005737 GO:0003677 GO:0003700 GO:0045892 GO:0000160 GO:0045893 GO:0006351
Gene3D	1.10.10.10
InterPro	IPR011006 IPR001867 IPR001789 IPR011991
Pfam	PF00072 PF00486
SMART	SM00448 SM00862
SUPFAM	SSF52172
PROSITE	PS50110

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0000156	phosphorelay response regulator activity	PMID:16176121^[1]	ECO:0001202			F	Figure 4 (G&H) Transcriptional regulatory protein Escherichia coli (strain K12) CpxR; phosphorelay response regulator. Response regulator member of the two-component regulatory system CpxA/CpxR	complete CACAO 13755
involved_in	GO:0010810	regulation of cell-substrate adhesion	PMID:11830644^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:15743952^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10020 EcoGene:EG10061 EcoGene:EG10731 EcoGene:EG11618 PANTHER:PTN000724188 UniProtKB:P9WGM1	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10020 EcoGene:EG10061 EcoGene:EG14045 PANTHER:PTN000724188	F	Seeded From UniProt	complete
enables	GO:0000156	phosphorelay response regulator activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10061 EcoGene:EG10672 EcoGene:EG11615 EcoGene:EG12615 PANTHER:PTN000724188 UniProtKB:O07776 UniProtKB:P37478 UniProtKB:Q9I2U3	F	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:9159398^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:7883164^[6]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:16077119^[7]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:15686558^[8]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:9159398^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:7883164^[6]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:16077119^[7]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:15686558^[8]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:18304323^[9]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:9159398^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:7883164^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:16077119^[7]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:15686558^[8]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001789 InterPro:IPR001867	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001867	F	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001867	P	Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0902	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
	GO:0045893	positive regulation of transcription, DNA-dependent	PMID:15743952^[3]	ECO:0000314			P	Fig 5.	complete CACAO 7514
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Skerker, JM et al. (2005) Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium: a system-level analysis. PLoS Biol. 3 e334 PubMed GONUTS page
↑ Otto, K & Silhavy, TJ (2002) Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 99 2287-92 PubMed GONUTS page
↑ ^3.0 ^3.1 Jubelin, G et al. (2005) CpxR/OmpR interplay regulates curli gene expression in response to osmolarity in Escherichia coli. J. Bacteriol. 187 2038-49 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Pogliano, J et al. (1997) Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev. 11 1169-82 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Danese, PN et al. (1995) The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP. Genes Dev. 9 387-98 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Batchelor, E et al. (2005) The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC. J. Bacteriol. 187 5723-31 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Hirakawa, H et al. (2005) Indole induces the expression of multidrug exporter genes in Escherichia coli. Mol. Microbiol. 55 1113-26 PubMed GONUTS page
↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page

[PMID:16176121-1] Skerker, JM et al. (2005) Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium: a system-level analysis. PLoS Biol. 3 e334 PubMed GONUTS page

[PMID:11830644-2] Otto, K & Silhavy, TJ (2002) Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 99 2287-92 PubMed GONUTS page

[PMID:15743952-3] 3.0 ^3.1 Jubelin, G et al. (2005) CpxR/OmpR interplay regulates curli gene expression in response to osmolarity in Escherichia coli. J. Bacteriol. 187 2038-49 PubMed GONUTS page

[PMID:21873635-4] 4.0 ^4.1 ^4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9159398-5] 5.0 ^5.1 ^5.2 Pogliano, J et al. (1997) Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev. 11 1169-82 PubMed GONUTS page

[PMID:7883164-6] 6.0 ^6.1 ^6.2 Danese, PN et al. (1995) The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP. Genes Dev. 9 387-98 PubMed GONUTS page

[PMID:16077119-7] 7.0 ^7.1 ^7.2 Batchelor, E et al. (2005) The Escherichia coli CpxA-CpxR envelope stress response system regulates expression of the porins ompF and ompC. J. Bacteriol. 187 5723-31 PubMed GONUTS page

[PMID:15686558-8] 8.0 ^8.1 ^8.2 Hirakawa, H et al. (2005) Indole induces the expression of multidrug exporter genes in Escherichia coli. Mol. Microbiol. 55 1113-26 PubMed GONUTS page

[PMID:18304323-9] Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

ECOLI:CPXR

Contents

Annotations

Notes

References

b

c

d

e

g

n

p

r

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools