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ECOLI:CODA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | codA | |
| Protein Name(s) | Cytosine deaminase
Cytosine aminohydrolase | |
| External Links | ||
| UniProt | P25524 | |
| EMBL | X63656 S56903 U73857 U00096 AP009048 | |
| PIR | S22662 | |
| RefSeq | NP_414871.1 YP_488631.1 | |
| PDB | 1K6W 1K70 1R9X 1R9Y 1R9Z 1RA0 1RA5 1RAK 3G77 3O7U 3R0D 3RN6 | |
| PDBsum | 1K6W 1K70 1R9X 1R9Y 1R9Z 1RA0 1RA5 1RAK 3G77 3O7U 3R0D 3RN6 | |
| ProteinModelPortal | P25524 | |
| SMR | P25524 | |
| DIP | DIP-9306N | |
| IntAct | P25524 | |
| MINT | MINT-1307853 | |
| STRING | 511145.b0337 | |
| PaxDb | P25524 | |
| PRIDE | P25524 | |
| EnsemblBacteria | AAC73440 BAE76119 | |
| GeneID | 12930819 944996 | |
| KEGG | ecj:Y75_p0326 eco:b0337 | |
| PATRIC | 32115805 | |
| EchoBASE | EB1302 | |
| EcoGene | EG11326 | |
| eggNOG | COG0402 | |
| HOGENOM | HOG000184778 | |
| InParanoid | P25524 | |
| KO | K01485 | |
| OMA | NNINVCF | |
| OrthoDB | EOG6QG8F9 | |
| PhylomeDB | P25524 | |
| BioCyc | EcoCyc:CYTDEAM-MONOMER ECOL316407:JW0328-MONOMER MetaCyc:CYTDEAM-MONOMER RETL1328306-WGS:GSTH-6950-MONOMER | |
| EvolutionaryTrace | P25524 | |
| PRO | PR:P25524 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P25524 | |
| GO | GO:0005829 GO:0004131 GO:0008198 GO:0042802 GO:0035888 GO:0008270 GO:0006209 | |
| Gene3D | 2.30.40.10 | |
| InterPro | IPR013108 IPR011059 | |
| Pfam | PF07969 | |
| SUPFAM | SSF51338 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0040029 |
regulation of gene expression, epigenetic |
ECO:0000270 |
P |
Figure 2 confirms that the NAC activation of codBA is direct and requires no other factors on codBA expression. |
complete | |||||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0035888 |
isoguanine deaminase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11326 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006209 |
cytosine catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11326 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11326 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004131 |
cytosine deaminase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11326 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0035888 |
isoguanine deaminase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008198 |
ferrous iron binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006209 |
cytosine catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004131 |
cytosine deaminase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016810 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004131 |
cytosine deaminase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0102480 |
5-fluorocytosine deaminase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019858 |
cytosine metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Muse, WB et al. (2003) Nitrogen regulation of the codBA (cytosine deaminase) operon from Escherichia coli by the nitrogen assimilation control protein, NAC. J. Bacteriol. 185 2920-6 PubMed GONUTS page
- ↑ 2.0 2.1 Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
- ↑ Ireton, GC et al. (2002) The structure of Escherichia coli cytosine deaminase. J. Mol. Biol. 315 687-97 PubMed GONUTS page
- ↑ Hitchcock, DS et al. (2011) Rescue of the orphan enzyme isoguanine deaminase. Biochemistry 50 5555-7 PubMed GONUTS page
- ↑ Hall, RS et al. (2011) Three-dimensional structure and catalytic mechanism of cytosine deaminase. Biochemistry 50 5077-85 PubMed GONUTS page
- ↑ 8.0 8.1 Porter, DJ & Austin, EA (1993) Cytosine deaminase. The roles of divalent metal ions in catalysis. J. Biol. Chem. 268 24005-11 PubMed GONUTS page
- ↑ de Haan, PG et al. (1972) Mapping of the gene for cytosine deaminase on the Escherichia coli chromosome. Antonie Van Leeuwenhoek 38 257-63 PubMed GONUTS page
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