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ECOLI:CAS1
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | ygbT (synonyms: cas1) | |
Protein Name(s) | CRISPR-associated endonuclease Cas1 | |
External Links | ||
UniProt | Q46896 | |
EMBL | U29579 U00096 AP009048 | |
PIR | G65056 | |
RefSeq | NP_417235.1 YP_490964.1 | |
PDB | 3NKD 3NKE 4P6I 4QDL | |
PDBsum | 3NKD 3NKE 4P6I 4QDL | |
ProteinModelPortal | Q46896 | |
SMR | Q46896 | |
DIP | DIP-12118N | |
IntAct | Q46896 | |
STRING | 511145.b2755 | |
PaxDb | Q46896 | |
EnsemblBacteria | AAC75797 BAE76832 | |
GeneID | 12932588 947228 | |
KEGG | ecj:Y75_p2693 eco:b2755 | |
PATRIC | 32120920 | |
EchoBASE | EB2915 | |
EcoGene | EG13114 | |
eggNOG | COG1518 | |
HOGENOM | HOG000015862 | |
InParanoid | Q46896 | |
KO | K15342 | |
OMA | FIHTGKP | |
OrthoDB | EOG60PHDG | |
BioCyc | EcoCyc:G7425-MONOMER ECOL316407:JW2725-MONOMER | |
PRO | PR:Q46896 | |
Proteomes | UP000000318 UP000000625 | |
Genevestigator | Q46896 | |
GO | GO:0005737 GO:0017108 GO:0008821 GO:0003677 GO:0046872 GO:0006974 GO:0051607 GO:0000737 GO:0006281 GO:0043571 | |
HAMAP | MF_01470 | |
InterPro | IPR002729 IPR019851 | |
Pfam | PF01867 | |
TIGRFAMs | TIGR00287 TIGR03638 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043571 |
maintenance of CRISPR repeat elements |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0017108 |
5'-flap endonuclease activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008821 |
crossover junction endodeoxyribonuclease activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004519 |
endonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004520 |
endodeoxyribonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043571 |
maintenance of CRISPR repeat elements |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051607 |
defense response to virus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004519 |
endonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078402 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051607 |
defense response to virus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078402 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078402 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043571 |
maintenance of CRISPR repeat elements |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078402 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004519 |
endonuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051607 |
defense response to virus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nuñez, JK et al. (2014) Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity. Nat. Struct. Mol. Biol. 21 528-34 PubMed GONUTS page
- ↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
- ↑ Yosef, I et al. (2012) Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli. Nucleic Acids Res. 40 5569-76 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Babu, M et al. (2011) A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol. Microbiol. 79 484-502 PubMed GONUTS page