GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:BSSS

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) bssS (synonyms: yceP)
Protein Name(s) Biofilm regulator BssS
External Links
UniProt P0AB33
EMBL U00096
AP009048
PIR A64849
RefSeq NP_415578.3
YP_489328.1
ProteinModelPortal P0AB33
IntAct P0AB33
STRING 511145.b1060
EnsemblBacteria AAC74144
BAA35857
GeneID 12931083
946104
KEGG ecj:Y75_p1030
eco:b1060
PATRIC 32117359
EchoBASE EB4081
EcoGene EG14335
eggNOG NOG12406
HOGENOM HOG000119007
KO K12148
OMA YILQAGI
OrthoDB EOG6677V9
BioCyc EcoCyc:G6557-MONOMER
ECOL316407:JW5152-MONOMER
PRO PR:P0AB33
Proteomes UP000000318
UP000000625
Genevestigator P0AB33
GO GO:1900190
InterPro IPR025730
Pfam PF13991
ProDom PD060858

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0090609

single-species submerged biofilm formation

PMID:16597943[1]

ECO:0000315

P

Culturing of yceP mutants and wild-type strain in LB did not lead to a variation in observed biofilm formation while twofold (P = 0.052) and threefold (P = 0.001) increases in biofilm occurred in LB glu upon deletion of yceP (Figure 1A). Lastly when biofilm formation was observed in a continuous flow system in M9C glu medium, the yceP deletion caused the cells to form a more random, scattered, and globular biofilm with far less surface coverage (Figure 2B).

complete
CACAO 3987

GO:1900191

negative regulation of single-species biofilm formation

PMID:23667443[2]

ECO:0000314

P

Table 4 demonstrates that Biofilm regulator BssS protein negatively regulates biofilm formation. This table illustrates that when biofilm is attacked by a pathogen and infected, the production of Biofilm regulator BssS protein or yceP protein is induced to stop further biofilm production. By regulating and halting the production of biofilm it stops the spread of the pathogen. So, therefore, we see that with BssS protein there is negative regulation in biofilm production in contrast to other proteins, which have the opposite effect on formation of biofilm, even when exposed to a pathogen.

complete
CACAO 9862

involved_in

GO:1900190

regulation of single-species biofilm formation

PMID:16597943[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1900190

regulation of single-species biofilm formation

PMID:14731270[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Domka, J et al. (2006) YliH (BssR) and YceP (BssS) regulate Escherichia coli K-12 biofilm formation by influencing cell signaling. Appl. Environ. Microbiol. 72 2449-59 PubMed GONUTS page
  2. Da Re, S et al. (2013) Identification of commensal Escherichia coli genes involved in biofilm resistance to pathogen colonization. PLoS ONE 8 e61628 PubMed GONUTS page
  3. Beloin, C et al. (2004) Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression. Mol. Microbiol. 51 659-74 PubMed GONUTS page