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ECOLI:BIOC

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) bioC
Protein Name(s) Malonyl-[acyl-carrier protein] O-methyltransferase

Malonyl-ACP O-methyltransferase Biotin synthesis protein BioC

External Links
UniProt P12999
EMBL J04423
A11534
U00096
AP009048
PIR A64814
RefSeq NP_415298.1
YP_489050.1
ProteinModelPortal P12999
SMR P12999
IntAct P12999
STRING 511145.b0777
PRIDE P12999
EnsemblBacteria AAC73864
BAE76364
GeneID 12930958
945388
KEGG ecj:Y75_p0750
eco:b0777
PATRIC 32116755
EchoBASE EB0117
EcoGene EG10119
eggNOG COG0500
HOGENOM HOG000265010
InParanoid P12999
KO K02169
OMA SHFRLEK
OrthoDB EOG6QRWCF
PhylomeDB P12999
BioCyc EcoCyc:EG10119-MONOMER
ECOL316407:JW0760-MONOMER
MetaCyc:EG10119-MONOMER
UniPathway UPA00078
PRO PR:P12999
Proteomes UP000000318
UP000000625
Genevestigator P12999
GO GO:0010340
GO:0009102
Gene3D 3.40.50.150
HAMAP MF_00835
InterPro IPR011814
IPR013216
IPR029063
Pfam PF08241
SUPFAM SSF53335
TIGRFAMs TIGR02072

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0019351

dethiobiotin biosynthetic process

PMID:20693992[1]

ECO:0000314

P

Figure 2 shows that bioC is necessary for the production of DTB.

complete
CACAO 4454

enables

GO:0010340

carboxyl-O-methyltransferase activity

PMID:20693992[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

PMID:4864413[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013216

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011814

P

Seeded From UniProt

complete

enables

GO:0010340

carboxyl-O-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011814

F

Seeded From UniProt

complete

enables

GO:0102130

malonyl-CoA methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.197

F

Seeded From UniProt

complete

enables

GO:0010340

carboxyl-O-methyltransferase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100313

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100313

P

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0093
UniPathway:UPA00078

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Lin, S et al. (2010) Biotin synthesis begins by hijacking the fatty acid synthetic pathway. Nat. Chem. Biol. 6 682-8 PubMed GONUTS page
  2. Del Campillo-Campbell, A et al. (1967) Biotin-requiring mutants of Escherichia coli K-12. J. Bacteriol. 94 2065-6 PubMed GONUTS page