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ECOLI:BIOB

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) bioB
Protein Name(s) Biotin synthase
External Links
UniProt P12996
EMBL J04423
A11530
U00096
AP009048
PIR JC2517
RefSeq NP_415296.1
YP_489048.1
PDB 1R30
PDBsum 1R30
ProteinModelPortal P12996
SMR P12996
DIP DIP-9220N
IntAct P12996
MINT MINT-1292998
STRING 511145.b0775
PaxDb P12996
PRIDE P12996
EnsemblBacteria AAC73862
BAE76362
GeneID 12930955
945370
KEGG ecj:Y75_p0748
eco:b0775
PATRIC 32116751
EchoBASE EB0116
EcoGene EG10118
eggNOG COG0502
HOGENOM HOG000239957
InParanoid P12996
KO K01012
OMA CGYCPQS
OrthoDB EOG622PMP
PhylomeDB P12996
BioCyc EcoCyc:BIOTIN-SYN-MONOMER
ECOL316407:JW0758-MONOMER
MetaCyc:BIOTIN-SYN-MONOMER
UniPathway UPA00078
EvolutionaryTrace P12996
PRO PR:P12996
Proteomes UP000000318
UP000000625
Genevestigator P12996
GO GO:0051537
GO:0051539
GO:0004076
GO:0005506
GO:0009102
Gene3D 3.20.20.70
HAMAP MF_01694
InterPro IPR013785
IPR010722
IPR002684
IPR024177
IPR006638
IPR007197
Pfam PF06968
PF04055
PIRSF PIRSF001619
SMART SM00876
SM00729
TIGRFAMs TIGR00433

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0051539

4 iron, 4 sulfur cluster binding

PMID:14967041[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0051537

2 iron, 2 sulfur cluster binding

PMID:14967041[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

PMID:4921685[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004076

biotin synthase activity

PMID:17014080[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006638
InterPro:IPR007197
InterPro:IPR013785

F

Seeded From UniProt

complete

enables

GO:0004076

biotin synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002684

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002684

P

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006638
InterPro:IPR007197

F

Seeded From UniProt

complete

enables

GO:0004076

biotin synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.8.1.6

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084161

P

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084161

F

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084161

F

Seeded From UniProt

complete

enables

GO:0004076

biotin synthase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000084161

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

enables

GO:0051537

2 iron, 2 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0001

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0009102

biotin biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0093
UniPathway:UPA00078

P

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Cosper, MM et al. (2004) Characterization of the cofactor composition of Escherichia coli biotin synthase. Biochemistry 43 2007-21 PubMed GONUTS page
  2. Rolfe, B (1970) Lambda phage transduction of the bio A locus of Escherichia coli. Virology 42 643-61 PubMed GONUTS page
  3. Lotierzo, M et al. (2006) Biotin synthase mechanism: mutagenesis of the YNHNLD conserved motif. Biochemistry 45 12274-81 PubMed GONUTS page