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ECOLI:ATPA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) atpA (ECO:0000255 with HAMAP-Rule:MF_01346) (synonyms: papA, uncA)
Protein Name(s) ATP synthase subunit alpha (ECO:0000255 with HAMAP-Rule:MF_01346)

ATP synthase F1 sector subunit alpha (ECO:0000255 with HAMAP-Rule:MF_01346) F-ATPase subunit alpha (ECO:0000255 with HAMAP-Rule:MF_01346)

External Links
UniProt P0ABB0
EMBL X01631
J01594
V00265
V00312
M12212
M25464
L10328
U00096
AP009048
V00266
PIR G65176
RefSeq NP_418190.1
YP_491695.1
PDB 1D8S
3OAA
PDBsum 1D8S
3OAA
ProteinModelPortal P0ABB0
SMR P0ABB0
DIP DIP-31845N
IntAct P0ABB0
MINT MINT-1251537
STRING 511145.b3734
TCDB 3.A.2.1.1
SWISS-2DPAGE P0ABB0
PaxDb P0ABB0
PRIDE P0ABB0
EnsemblBacteria AAC76757
BAE77554
GeneID 12932824
948242
KEGG ecj:Y75_p3434
eco:b3734
PATRIC 32122965
EchoBASE EB0096
EcoGene EG10098
eggNOG COG0056
HOGENOM HOG000130111
InParanoid P0ABB0
KO K02111
OMA EDGTEGI
OrthoDB EOG67X1S1
PhylomeDB P0ABB0
BioCyc EcoCyc:ATPA-MONOMER
ECOL316407:JW3712-MONOMER
MetaCyc:ATPA-MONOMER
EvolutionaryTrace P0ABB0
PRO PR:P0ABB0
Proteomes UP000000318
UP000000625
Genevestigator P0ABB0
GO GO:0016020
GO:0005886
GO:0045261
GO:0005524
GO:0046933
GO:0046961
GO:0015991
GO:0015986
GO:0042777
Gene3D 2.40.30.20
3.40.50.300
HAMAP MF_01346
InterPro IPR020003
IPR023366
IPR005294
IPR000793
IPR000194
IPR004100
IPR018538
IPR027417
PANTHER PTHR15184:SF3
Pfam PF00006
PF00306
PF09378
SUPFAM SSF47917
SSF50615
SSF52540
TIGRFAMs TIGR00962
PROSITE PS00152

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0016020

membrane

PMID:16858726[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88115
PANTHER:PTN000389891
UniProtKB:P25705

F

Seeded From UniProt

complete

enables

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88115
PANTHER:PTN000389891
SGD:S000000195
UniProtKB:P25705

F

Seeded From UniProt

complete

part_of

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10098
PANTHER:PTN000389972

C

Seeded From UniProt

complete

enables

GO:0043531

ADP binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000389891
RGD:619993

F

Seeded From UniProt

complete

contributes_to

GO:0016887

ATPase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000389891
RGD:619993
SGD:S000000195
UniProtKB:P25705

F

Seeded From UniProt

complete

involved_in

GO:0015986

ATP synthesis coupled proton transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10098
PANTHER:PTN000389891
SGD:S000000195

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000389972
UniProtKB:P9WPU7

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88115
PANTHER:PTN000389891
RGD:619993

F

Seeded From UniProt

complete

part_of

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

PMID:153904[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015986

ATP synthesis coupled proton transport

PMID:4256722[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0046933

P

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0046933

P

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0046933

P

Seeded From UniProt

complete

involved_in

GO:0099132

ATP hydrolysis coupled cation transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0046933

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000194
InterPro:IPR020003

F

Seeded From UniProt

complete

involved_in

GO:0015986

ATP synthesis coupled proton transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000793
InterPro:IPR005294

P

Seeded From UniProt

complete

enables

GO:0032559

adenyl ribonucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033732

F

Seeded From UniProt

complete

part_of

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005294

C

Seeded From UniProt

complete

involved_in

GO:0046034

ATP metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004100
InterPro:IPR036121

P

Seeded From UniProt

complete

enables

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005294

F

Seeded From UniProt

complete

involved_in

GO:1902600

proton transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004100
InterPro:IPR036121

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101844

C

Seeded From UniProt

complete

enables

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101844

F

Seeded From UniProt

complete

involved_in

GO:0015986

ATP synthesis coupled proton transport

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101844

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101844

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0997
UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0139

C

Seeded From UniProt

complete

involved_in

GO:0006754

ATP biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0066

P

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. ↑ Kanazawa, H et al. (1978) Coupling factor ATPase from Escherichia coli. An uncA mutant (uncA401) with defective alpha subunit. J. Biochem. 84 1513-7 PubMed GONUTS page
  4. ↑ Butlin, JD et al. (1971) Oxidative phosphorylation in Escherichia coli K12. Mutations affecting magnesium ion- or calcium ion-stimulated adenosine triphosphatase. Biochem. J. 124 75-81 PubMed GONUTS page
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