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ECOLI:AROF

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) aroF
Protein Name(s) Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase DAHP synthase Phospho-2-keto-3-deoxyheptonate aldolase

External Links
UniProt P00888
EMBL K01989
M10431
U00096
AP009048
M60890
K03453
PIR I41141
RefSeq NP_417092.1
YP_490824.1
ProteinModelPortal P00888
SMR P00888
DIP DIP-9154N
IntAct P00888
STRING 511145.b2601
SWISS-2DPAGE P00888
PaxDb P00888
PRIDE P00888
EnsemblBacteria AAC75650
BAA16487
GeneID 12934476
947084
KEGG ecj:Y75_p2549
eco:b2601
PATRIC 32120601
EchoBASE EB0076
EcoGene EG10078
eggNOG COG0722
HOGENOM HOG000220501
InParanoid P00888
KO K01626
OMA TIADIIH
OrthoDB EOG63JR9W
PhylomeDB P00888
BioCyc EcoCyc:AROF-MONOMER
ECOL316407:JW2582-MONOMER
MetaCyc:AROF-MONOMER
UniPathway UPA00053
PRO PR:P00888
Proteomes UP000000318
UP000000625
Genevestigator P00888
GO GO:0003849
GO:0042802
GO:0009073
GO:0009423
Gene3D 3.20.20.70
InterPro IPR013785
IPR006218
IPR006219
PANTHER PTHR21225
Pfam PF00793
PIRSF PIRSF001361
TIGRFAMs TIGR00034

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009073

aromatic amino acid family biosynthetic process

PMID:15575692[1]

ECO:0000315

P

Figure 3

complete

involved_in

GO:0009073

aromatic amino acid family biosynthetic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10078
EcoGene:EG10080
PANTHER:PTN000476971
UniProtKB:A0A1D8PGI8

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10080
PANTHER:PTN000476971

C

Seeded From UniProt

complete

enables

GO:0003849

3-deoxy-7-phosphoheptulonate synthase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10078
EcoGene:EG10079
EcoGene:EG10080
PANTHER:PTN000476971
SGD:S000000453
SGD:S000002442
UniProtKB:A0A1D8PGI8
UniProtKB:C8VTT5
UniProtKB:G5EB34

F

Seeded From UniProt

complete

involved_in

GO:0009073

aromatic amino acid family biosynthetic process

PMID:15575692[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:9387[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009073

aromatic amino acid family biosynthetic process

PMID:15575692[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003849

3-deoxy-7-phosphoheptulonate synthase activity

PMID:9387[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013785

F

Seeded From UniProt

complete

enables

GO:0003849

3-deoxy-7-phosphoheptulonate synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006219

F

Seeded From UniProt

complete

involved_in

GO:0009058

biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006218

P

Seeded From UniProt

complete

involved_in

GO:0009073

aromatic amino acid family biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006219

P

Seeded From UniProt

complete

enables

GO:0003849

3-deoxy-7-phosphoheptulonate synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.54

F

Seeded From UniProt

complete

involved_in

GO:0008652

cellular amino acid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0028

P

Seeded From UniProt

complete

involved_in

GO:0009073

aromatic amino acid family biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0057

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0009423

chorismate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00053

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Oldiges, M et al. () Stimulation, monitoring, and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway. Biotechnol. Prog. 20 1623-33 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Schoner, R & Herrmann, KM (1976) 3-Deoxy-D-arabino-heptulosonate 7-phosphate synthase. Purification, properties, and kinetics of the tyrosine-sensitive isoenzyme from Escherichia coli. J. Biol. Chem. 251 5440-7 PubMed GONUTS page