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ECOLI:ARLY

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) argH (ECO:0000255 with HAMAP-Rule:MF_00006)
Protein Name(s) Argininosuccinate lyase (ECO:0000255 with HAMAP-Rule:MF_00006)

ASAL (ECO:0000255 with HAMAP-Rule:MF_00006) Arginosuccinase (ECO:0000255 with HAMAP-Rule:MF_00006)

External Links
UniProt P11447
EMBL U00006
U00096
AP009048
M21446
J01590
PIR C65203
RefSeq NP_418395.1
YP_491492.1
PDB 1TJ7
PDBsum 1TJ7
ProteinModelPortal P11447
SMR P11447
DIP DIP-9142N
STRING 511145.b3960
PaxDb P11447
PRIDE P11447
EnsemblBacteria AAC76942
BAE77351
GeneID 12934472
948463
KEGG ecj:Y75_p3228
eco:b3960
PATRIC 32123441
EchoBASE EB1205
EcoGene EG11223
eggNOG COG0165
HOGENOM HOG000242744
InParanoid P11447
KO K01755
OMA ATDFRLW
OrthoDB EOG6P5ZF8
PhylomeDB P11447
BioCyc EcoCyc:ARGSUCCINLYA-MONOMER
ECOL316407:JW3932-MONOMER
MetaCyc:ARGSUCCINLYA-MONOMER
UniPathway UPA00068
EvolutionaryTrace P11447
PRO PR:P11447
Proteomes UP000000318
UP000000625
Genevestigator P11447
GO GO:0005737
GO:0004056
GO:0042450
Gene3D 1.10.275.10
HAMAP MF_00006
InterPro IPR029419
IPR009049
IPR024083
IPR020557
IPR000362
IPR022761
IPR008948
PANTHER PTHR11444
PTHR11444:SF3
Pfam PF14698
PF00206
PRINTS PR00149
SUPFAM SSF48557
TIGRFAMs TIGR00838
PROSITE PS00163

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042450

arginine biosynthetic process via ornithine

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000154674
SGD:S000001060

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000154674
RGD:619974

C

Seeded From UniProt

complete

enables

GO:0004056

argininosuccinate lyase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11223
PANTHER:PTN000154674
PomBase:SPBC1773.14
RGD:619974
SGD:S000001060
UniProtKB:P04424

F

Seeded From UniProt

complete

enables

GO:0004056

argininosuccinate lyase activity

PMID:6762207[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008948
InterPro:IPR020557

F

Seeded From UniProt

complete

enables

GO:0004056

argininosuccinate lyase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009049

F

Seeded From UniProt

complete

involved_in

GO:0042450

arginine biosynthetic process via ornithine

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009049

P

Seeded From UniProt

complete

enables

GO:0004056

argininosuccinate lyase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.3.2.1

F

Seeded From UniProt

complete

involved_in

GO:0006526

arginine biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000037443

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000037443

C

Seeded From UniProt

complete

enables

GO:0004056

argininosuccinate lyase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000037443

F

Seeded From UniProt

complete

involved_in

GO:0008652

cellular amino acid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0028

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006526

arginine biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0055
UniPathway:UPA00068

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Zidwick, MJ & Rogers, P (1982) The determination by radiochemical assay of argininosuccinase produced in an Escherichia coli system in vitro. Biochem. J. 207 529-33 PubMed GONUTS page